Gene flow and the coevolution of parasite range

基因流和寄生虫范围的共同进化

• 批准号: 6626002
• 负责人: SCOTT L NUISMER
• 金额: $ 1.32万
• 依托单位: UNIVERSITY OF TEXAS AT AUSTIN
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-03-01 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6626002
• 关键词: communicable disease transmission; disease /disorder proneness /risk; evolution; gene environment interaction; genetic models; geographic site; host organism interaction; mathematical model; mathematics; microorganism genetics; microorganism growth; microorganism population study; model design /development

DESCRIPTION (provided by applicant): The proposed research will develop new mathematical models that incorporate both demography and coevolution into spatially structured host-parasite interactions. Because these new models will allow mathematical analysis, they represent a substantial advance over past work that has relied exclusively on numerical simulations. Analysis of these models will elucidate the role that gene flow and coevolution play in shaping the geographic distributions and range limits of parasites. In addition, the results will generate testable predictions for how changes in rates of gene flow alter the equilibrium sizes of parasite geographic ranges. These predictions become increasingly important as natural patterns of gene flow become disrupted through habitat fragmentation, potentially leading to range expansions of parasites and infectious diseases.

描述（由申请人提供）：拟议的研究将开发新的 数学模型将人口统计学和协同进化纳入 空间结构的宿主 - 寄生虫相互作用。因为这些新型号将 允许数学分析，它们代表了过去的实质性进步 仅依赖数值模拟的工作。这些分析 模型将阐明基因流量和协同进化在塑造中的作用 寄生虫的地理分布和范围限制。另外， 结果将对基因率的变化产生可测试的预测 流动改变了寄生虫地理范围的平衡大小。这些 随着基因流的自然模式，预测变得越来越重要 通过栖息地破碎而破坏，可能导致范围 寄生虫和传染病的扩张。

项目成果

Coevolution in temporally variable environments.

时间变化环境中的共同进化。

• DOI: 10.1086/376582
• 发表时间: 2003
• 期刊: The American naturalist.
• 作者: Nuismer,ScottL;Gomulkiewicz,Richard;Morgan,MartinT
• 通讯作者: Morgan,MartinT

Gene flow and the coevolution of parasite range.

基因流和寄生虫范围的共同进化。

• DOI: 10.1111/j.0014-3820.2003.tb00286.x
• 发表时间: 2003
• 期刊: Evolution; international journal of organic evolution
• 作者: Nuismer,ScottL;Kirkpatrick,Mark
• 通讯作者: Kirkpatrick,Mark