CLINICAL RESEARCH IN SUPPORTIVE CARE FOR CANCER

描述：(申请者描述)本研究的职业发展 获奖申请侧重于临床研究的方法 癌症的支持性护理。具体目标是：1)加强 制定申请人的癌症支持性护理研究计划； 2)帮助培训新的临床研究人员进行支持性护理 癌症；以及3)在以下领域建立协作的跨学科研究 支持性护理。对癌症支持性护理的关注建立在 申请人有广泛的前期工作，职业目标是改善对人的关怀 与癌症和癌症风险有关的问题，并解决了当前的重要关切 关于癌症护理的质量。最近，领先的癌症护理组织 确定了对症状管理、行为研究的需求 问题、心理社会反应和癌症存活期的经历。 在这个项目中进行临床研究的调查员队伍 领域是有限的，未来的进展取决于将资源投入到 研究、培训和发展。申请人有很强的记录 成功进行临床研究培训，指导博士后和博士后 学生们通过启动他们的独立职业生涯，进行高 癌症支持护理领域的高质量临床研究，以及 建立协作的跨学科关系。申请人的 目前的工作是在癌症治疗(PI)后进行调整，疲劳 治疗过程中的管理(协查人员)，以及与摄取 高中生成人和儿童结肠镜筛查及基因检测 结肠癌风险(K07赞助商)。本申请中提出的一项研究是 检查疲劳程度、血液学改变之间的关系 对骨髓抑制化疗和其他治疗副作用的反应 和症状。这项研究解决了关于以下问题的一个重要认识差距 影响人们产生疲劳感的因素 正在接受积极的癌症治疗。此应用程序利用新的 亨斯迈癌症研究所(HCI)的方案倡议与 随着HCI临床癌症护理服务的巩固。

DESCRIPTION: (Applicant's Description) This Research Career Development Award application focuses on clinical investigation of approaches to supportive care in cancer. The specific aims are to: 1) enhance the development of the applicant's program of research in cancer supportive care; 2) contribute to the training of new clinical investigators in supportive care for cancer; and 3) build collaborative interdisciplinary research efforts in supportive care. The focus on supportive care for cancer builds on the applicant's extensive prior work, career goal of improving the care of people with cancer and at risk for cancer, and addresses important current concerns about the quality of cancer care. Recently, leading cancer care organizations have identified the need for research on symptom management, behavioral issues, psychosocial responses, and the experience of cancer survivorship. The pool of investigators conducting programs of clinical research in this area is limited and future progress is contingent upon devoting resources to research training and development. The applicant has a strong record of success in clinical research training, mentoring predoctoral and postdoctoral students through to the launch of their independent careers, conducting high quality clinical research in the area of supportive care for cancer, and establishing collaborative interdisciplinary relationships. The applicant's current work is on adjustment following cancer treatment (PI), fatigue management during treatment (coinvestigator), and factors related to uptake of colonoscopic screening and genetic testing among adults and children at high risk for colon cancer (K07 sponsor). A study proposed in this application is to examine relationships among perceived level of fatigue, hematologic changes in response to myelosuppressive chemotherapy, and other treatment side effects and symptoms. This study addresses an important gap in knowledge about factors contributing to perceptions of fatigue experienced by people undergoing active cancer treatment. This application takes advantage of new programmatic initiatives at the Huntsman Cancer Institute (HCI) and coincides with the consolidation of clinical cancer care services at HCI.