CLINICAL RESEARCH IN SUPPORTIVE CARE FOR CANCER

癌症支持治疗的临床研究

• 批准号: 6798199
• 负责人: LILLIAN M. NAIL
• 金额: $ 11.54万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-01 至 2006-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6798199
• 关键词: adenomatous polyps; behavioral /social science research tag; breast neoplasms; clinical research; colorectal neoplasms; coping; drug adverse effect; emotional adjustment; endoscopy; fatigue; gastrointestinal imaging /visualization; genetic disorder diagnosis; health care quality; human subject; lung neoplasms; neoplasm /cancer chemotherapy; neoplasm /cancer radiation therapy; oncology nursing; patient care; psychological aspect of cancer; quality of life; social psychology; telecommunications

DESCRIPTION: (Applicant's Description) This Research Career Development Award application focuses on clinical investigation of approaches to supportive care in cancer. The specific aims are to: 1) enhance the development of the applicant's program of research in cancer supportive care; 2) contribute to the training of new clinical investigators in supportive care for cancer; and 3) build collaborative interdisciplinary research efforts in supportive care. The focus on supportive care for cancer builds on the applicant's extensive prior work, career goal of improving the care of people with cancer and at risk for cancer, and addresses important current concerns about the quality of cancer care. Recently, leading cancer care organizations have identified the need for research on symptom management, behavioral issues, psychosocial responses, and the experience of cancer survivorship. The pool of investigators conducting programs of clinical research in this area is limited and future progress is contingent upon devoting resources to research training and development. The applicant has a strong record of success in clinical research training, mentoring predoctoral and postdoctoral students through to the launch of their independent careers, conducting high quality clinical research in the area of supportive care for cancer, and establishing collaborative interdisciplinary relationships. The applicant's current work is on adjustment following cancer treatment (PI), fatigue management during treatment (coinvestigator), and factors related to uptake of colonoscopic screening and genetic testing among adults and children at high risk for colon cancer (K07 sponsor). A study proposed in this application is to examine relationships among perceived level of fatigue, hematologic changes in response to myelosuppressive chemotherapy, and other treatment side effects and symptoms. This study addresses an important gap in knowledge about factors contributing to perceptions of fatigue experienced by people undergoing active cancer treatment. This application takes advantage of new programmatic initiatives at the Huntsman Cancer Institute (HCI) and coincides with the consolidation of clinical cancer care services at HCI.

描述：（申请人的描述）本研究职业发展 奖项申请侧重于临床研究的方法， 癌症的支持治疗 具体目标是：1）加强 发展申请人在癌症支持治疗方面的研究计划; 2)有助于培训新的临床研究者进行支持性治疗 癌症;和3）建立合作的跨学科研究工作， 支持性护理。 对癌症支持性护理的关注建立在 申请人以前的广泛工作，职业目标是改善对人的照顾 癌症和癌症风险，并解决当前重要的问题， 癌症治疗的质量。 最近，领先的癌症护理组织 已经确定了对症状管理，行为 问题，心理社会反应和癌症生存的经验。 在这方面进行临床研究项目的研究者库 区域有限，未来的进展取决于将资源用于 研究、培训和发展。 申请人有良好的记录， 在临床研究培训、指导博士前和博士后方面取得成功 学生通过开展自己的独立职业生涯，进行高 在癌症支持治疗领域开展高质量的临床研究， 建立跨学科合作关系。 申请人的 目前的工作是调整后的癌症治疗（PI），疲劳 治疗期间的管理（合作研究者），以及与 结肠镜筛查和基因检测的成人和儿童在高 结肠癌风险（K 07申办者）。 本申请中提出的一项研究是 检查疲劳程度、血液学变化 对骨髓抑制化疗和其他治疗副作用的反应 和症状。 这项研究解决了一个重要的知识差距， 导致人们感觉疲劳的因素 正在接受积极的癌症治疗 该应用程序利用新的 亨斯迈癌症研究所（HCI）的计划举措， 随着HCI临床癌症护理服务的巩固。