CORE--ANIMAL CHARACTERIZATION CORE

描述（由申请人提供）：试点项目组成部分将持续到印第安纳酒精研究中心（IARC）第16-20年（2002-2007年）。这一组成部分是一种机制，用于资助有前途的创新研究项目，吸引新的研究人员进入酒精研究领域，开发新的方法，以及探索可能与国际癌症研究机构总体目标相关的领域。试点项目机制固有的灵活性使国际癌症研究机构能够在独特的科学机会出现时迅速作出反应，并支持具有良好潜力的研究项目，使其发展成为外部资助的研究项目。在过去的14年里，IARC试点项目对印第安纳大学校园酒精研究的发展产生了明显的强烈刺激作用。我们认为，在获得国际癌症研究机构的试点资金之后，无论是新的研究人员还是从事新的酒精相关研究的更资深的科学家，在获得独立的校外资金方面都取得了显著的成功

DESCRIPTION (provided by applicant): The Pilot Project Component will continue through years 16-20 (2002-2007) of the Indiana Alcohol Research Center (IARC). This Component is a mechanism for funding promising, innovative research projects, for attracting new investigators to the alcohol research field, for developing new methodologies, and for exploring areas of potential relevance to the overall aims of the IARC. The flexibility inherent in the Pilot Project mechanism has allowed the IARC to respond rapidly to unique scientific opportunities as they have arisen and to support research projects with good potential for evolving into extramurally funded research programs. The IARC Pilot Project Component has had a demonstrably strong stimulatory effect on the growth of alcohol research on the IU campus over the past 14 years. We believe that there has been a remarkable rate of success in obtaining independent extramural funding, subsequent to the receipt of IARC pilot funding, for both new investigators as well as for more senior scientists who have entered new alcohol-related research arenas. Based on past performance, we anticipate that this component will result in continued growth of the lARC research program in important new directions. The Administrative Core will provide oversight for the pilot projects which are managed in the Pilot Project Component under the direction of Jan Froehlich with input from Dave Crabb, T.-K. Li, Sean O'Connor and the External Advisory Committee.