CORE--ANIMAL CHARACTERIZATION CORE

核心——动物表征核心

• 批准号: 7550803
• 负责人: SUSANNA R KELLER
• 金额: $ 13.41万
• 依托单位: UNIVERSITY OF VIRGINIA
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-02-01 至 2008-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7550803
• 关键词: biological signal transduction; biomedical facility; blood pressure; diabetes mellitus; genetically modified animals; glucose clamp technique; glucose metabolism; heart rate; insulin; insulin sensitivity /resistance; laboratory mouse; laboratory rat; magnetic resonance imaging; northern blottings; pancreatic islet function; photon absorptiometry; western blottings

DESCRIPTION (provided by applicant): The Pilot Project Component will continue through years 16-20 (2002-2007) of the Indiana Alcohol Research Center (IARC). This Component is a mechanism for funding promising, innovative research projects, for attracting new investigators to the alcohol research field, for developing new methodologies, and for exploring areas of potential relevance to the overall aims of the IARC. The flexibility inherent in the Pilot Project mechanism has allowed the IARC to respond rapidly to unique scientific opportunities as they have arisen and to support research projects with good potential for evolving into extramurally funded research programs. The IARC Pilot Project Component has had a demonstrably strong stimulatory effect on the growth of alcohol research on the IU campus over the past 14 years. We believe that there has been a remarkable rate of success in obtaining independent extramural funding, subsequent to the receipt of IARC pilot funding, for both new investigators as well as for more senior scientists who have entered new alcohol-related research arenas. Based on past performance, we anticipate that this component will result in continued growth of the lARC research program in important new directions. The Administrative Core will provide oversight for the pilot projects which are managed in the Pilot Project Component under the direction of Jan Froehlich with input from Dave Crabb, T.-K. Li, Sean O'Connor and the External Advisory Committee.

描述（由申请人提供）：试点项目的组成部分将继续通过年16-20（2002-2007）的印第安纳州酒精研究中心（IARC）。该部分是一个机制，用于资助有前途的创新研究项目，吸引新的研究人员进入酒精研究领域，开发新的方法，并探索与IARC总体目标潜在相关的领域。试点项目机制固有的灵活性使IARC能够对出现的独特科学机会迅速作出反应，并支持具有发展成为校外资助研究计划的良好潜力的研究项目。在过去的14年里，IARC试点项目组件对IU校园内酒精研究的增长产生了明显的强烈刺激作用。我们相信，在获得国际癌症研究机构试点资金之后，无论是新的研究人员还是进入新的酒精相关研究的资深科学家， 竞技场根据过去的表现，我们预计这一组成部分将导致lARC研究计划在重要的新方向上持续增长。行政核心将在Jan Froehlich的指导下，在Dave Crabb，T.的投入下，对试点项目部分管理的试点项目进行监督。K.李，肖恩奥康纳和外部咨询委员会。