A 3-D Interactive Atlas of the Maxilla, Mandible & TMJ

描述：该项目将制作具有一定分辨率的解剖结构模型，由于技术限制，这在以前是不可能的。可见人项目(VHP)是使用连续横截面来构建体素模型的第一个演示。虽然VHP是一项里程碑式的工作，但它存在样本量有限、(两个受试者)、分辨率和分割问题。该项目将增加样本大小，并将以显著更高的分辨率收集数据。然后，它将集中在特定的解剖部分-TMJ，以说明正常和异常的解剖样本，并演示关节的功能运动。第一个目标是定义上颌、下颌、TMJ和周围组织的解剖、血管、神经、肌肉和骨骼。我们将使用在第一阶段拨款期间完善的数据收集方法。查看协议将被扩展，允许我们分割、移除和替换各种结构。除此之外，我们还将把CT、MRI和数字摄影数据联系起来，以便更好地了解解剖结构。所有的模型都将是完全交互的，可绕六个轴旋转，带有注释，能够分段关闭和打开，并以立体方式查看。第二个目的是通过包含来自加州大学旧金山分校的一个重要头骨集合的扫描数据来说明TMJ的病理。第三个目标是编制一份全面的TMJ地图集。它将包括关节的宏观解剖，包括关节囊解剖、神经支配、血管和相关的咀嚼肌肉。观众将能够通过它的所有运动移动带注释的关节，并观察肌肉在咀嚼和下颌运动中是如何工作的。以高分辨率成像解剖的小的离散区域的能力提供了有用的数据，这是教育和临床上有用的，是对全面的高分辨率文库的重要贡献。该地图集将供医学和牙科学生、口腔和颌面外科医生、放射科医生、整形外科医生和耳鼻喉科医生使用。

DESCRIPTION: This project will produce models of anatomical structures with a degree of resolution that, because of technological limitations, has not been previously possible. The Visible Human Project (VHP) was the first demonstration of the use of serial cross sections to build voxel models. While the VHP represent a landmark effort, it suffers from limited sample size, (two subjects), resolution and segmentation problems. This project will increase the sample size and will collect data at a dramatically higher resolution. It will then concentrate on a specific piece of anatomy - the TMJ, to illustrate normal and abnormal anatomical samples and to demonstrate the functional movements of the joint. The first Aim is to define the anatomy, vascularity, innervation, muscle, and bone of the maxilla, mandible, TMJ and surrounding tissue. We will use data collection methods perfected during the Phase I grant. Viewing protocols will be expanded, allowing us to segment, remove and replace various structures. Ancillary to this, we will correlate the CT, MRI and digital photographic data for a better understanding of the anatomy. All of the models will be fully interactive, rotatable around six axes, annotated, capable of being turned off and on segmentally and viewed in stereo. The second Aim is to illustrate the pathology of the TMJ by the inclusion of scanned data of an important collection of skulls from UCSF. The third Aim is to develop a comprehensive Atlas of the TMJ. It will include the macroanatomy of the joint including the capsular anatomy, innervation, vascularity and the associated muscles of mastication. The viewer will be able to move the annotated joint through all of its movements and observe how the musculature works in both mastication and mandibular movements. The ability to image small discrete areas of anatomy at high resolution provides useful data that is educational and clinically useful and is an important contribution to a comprehensive high-resolution library. The Atlas will be designed to be used by medical and Dental students, oral and maxillofacial surgeons, radiologists, plastic and ENT surgeons.