Career Development Award in International Women's Health

描述（由申请人提供）：本申请是福格蒂国际中心伊丽莎白·斯金格博士的国际研究科学家发展奖的竞争性更新。Stringer博士要求再给予2年的支持，以便她能够继续朝着成为国际妇女健康和临床流行病学领域一名能干和富有成效的独立研究人员的目标努力。这一目标将通过以下活动来实现：1)完成伦敦热带医学与卫生学院的流行病学硕士学位；2)完成她在Fogarty IRSDA初始阶段成功实施的随机试验的长期随访部分；3)在她的专家导师的帮助下，对随机试验进行三个亚分析；4)对影响赞比亚妇女利用预防母婴艾滋病毒传播服务的因素进行多地点观察研究。在为期两年的资助期结束时，候选人将在设计和实施随机介入试验和大型观察性多地点研究方面具有丰富的现场经验，并获得著名大学的流行病学资格。此外，在导师的指导下，她将有机会将理论与实践相结合，并对收集到的数据采用各种分析技术，包括介入试验中的意向比例分析和纵向/生存分析，重复测量技术和分层混合建模。她还将建立两个可供分析的大型流行病学数据库。在她额外的2年支持结束时，Stringer博士将准备并提交R01或其他独立资助的个人研究者申请。

DESCRIPTION (provided by applicant): This application is for a competitive renewal of Dr. Elizabeth Stringer's International Research Scientist Development Award from the Fogarty International Center. Dr. Stringer requests an additional 2 years of support so that she can continue working toward her goal of becoming a competent and productive independent researcher in international women's health and clinical epidemiology. This goal will be pursued through the following activities: 1) completion of the MSc degree in epidemiology from the London School of Tropical Medicine and Hygiene; 2) completion of the long term follow-up portion of the randomized trial she successfully implemented during the initial portion of her Fogarty IRSDA; 3) conduct of three subanalyses from the randomized trial with assistance from her expert mentors; 4) conduct of a multi-site observational study of factors affecting women's utilization of services to prevent mother-to-child HIV transmission in Zambia. At the end of the 2-year grant period, the candidate will have substantial field experience in the design and conduct of both a randomized interventional trial and a large observational multi-site study and a qualification in epidemiology from a distinguished university. In addition, she will have had the opportunity, under the direction of her mentors, to merge the theoretical and the practical, and employ a variety of analytical techniques to the data she has gathered, including intent-to-treat proportional analysis and longitudinal/survival analysis in an interventional trial, techniques in repeated measures, and hierarchical mixed modeling. She will also have established two large epidemiological databases that will be available for analysis. At the end of her additional 2 years of support, Dr. Stringer will prepare and submit an R01 or other individual investigator application for independent funding.