HIV Neuroprotection Workshop

描述（由申请人提供）：本申请为2004年9月10日至14日在意大利撒丁岛举行的第六届国际神经病毒学研讨会同时举行的HIV神经保护研讨会寻求支持。本次会议在美国以外的地方举行，会议的目的是汇集世界上人类免疫缺陷病毒（HIV）感染的神经、神经心理学和精神并发症的病理生理机制和临床表现方面的专家。本次会议将主要但不限于以下内容：1)HIV引起的神经系统疾病的临床方面，(2)HIV神经发病机制的分子和细胞方面，(3)信号转导和神经保护中的病毒和细胞蛋白，(4)艾滋病国际圆桌会议，(5)艾滋病中的神经免疫相互作用。与其他神经退行性疾病和发育治疗的相关性，(6)神经毒性病毒蛋白和细胞间通讯，以及(7)神经成像和艾滋病。已经为每一个主题确定了全体会议发言人。这次会议是传播这些主题新信息的有效途径，并促进不同研究团队之间的新调查途径和合作。会议还将为鼓励这一学科的初级研究人员提供有效途径。伯杰博士作为会议组织者有着良好的记录。他是艾滋病神经科学会议的联合创始人和联合主席。在组织这次研讨会时，伯杰和波梅兰茨得到了一群杰出的国际权威人士的帮助，他们研究的是艾滋病毒/艾滋病的神经科学，还有意大利神经艾滋病科学家的当地组织委员会。要求支助行政援助、全体会议发言人的旅费、见习奖学金和出版费。这次会议是第一次强调HIV CNS和PNS疾病的神经保护。通过将这次会议与国际神经病毒学研讨会结合起来，这种协同作用可以得到利用。

DESCRIPTION (provided by applicant): This application seeks support for the conference entitled HIV Neuroprotection Workshop to be held in conjunction with the 6th International Symposium on Neurovirology in Sardinia, Italy during September 10th- 14th, 2004. This conference is being held outside the U.S. The purpose of the conference is to bring together the world's experts in the pathophysiological mechanisms and clinical manifestations of the neurological, neuropsychological, and psychiatric complications of human immunodeficiency virus (HIV) infection. This conference will focus chiefly, but not exclusively, on the following: 1) clinical aspects of neurologic disease caused by HIV, (2) molecular and cellular aspects of HIV neuropathogenesis, (3) viral and cellular proteins in signal transduction and neuroprotection, (4) AIDS international roundtable, (5) Neuroimune interactions in AIDS: relevance to other neurodegenerative diseases and developmental therapeutics, (6) neurotoxic viral proteins and intercellular communications, and (7) neuroimaging and AIDS. Plenary speakers have been identified for each of these topics. This conference serves as efficient means to disseminate new information on these topics as well as to foster new avenues of investigation and collaborations between different research teams. The conference will also provide an effective avenue for encouraging junior investigators in this discipline. Dr. Berger has an established track record as a conference organizer. He is the co-founder and co-chair of the Neuroscience of HIV Meeting. In organizing this workshop, Drs. Berger and Pomerantz have the assistance of a distinguished group of international authorities on the neuroscience of HIV/AIDS in addition to the local organizing committee of Italian neuroAIDS scientists. Support is requested for administrative assistance, travel for plenary speakers, trainee scholarships, and publication costs. The proposed conference is the first of its kind to highlight neuroprotection in HIV CNS and PNS disorders. By coupling this meeting with the International Symposium on Neurovirology this synergy can be exploited.