HIV Neuroprotection Workshop

描述（由申请人提供）：本申请寻求对将于2004年9月10日至14日在意大利撒丁岛举行的第六届神经病毒学国际研讨会上举行的题为“HIV神经保护研讨会”的会议的支持。本次会议是在美国以外举行的会议的目的是汇集世界各地的专家在人类免疫缺陷病毒（HIV）感染的神经，神经心理和精神并发症的病理生理机制和临床表现。本次会议将主要关注以下内容，但不限于此：（1）HIV引起的神经系统疾病的临床方面，（2）HIV神经发病机制的分子和细胞方面，（3）信号转导和神经保护中的病毒和细胞蛋白，（4）艾滋病国际圆桌会议，（5）艾滋病中的神经免疫相互作用：与其他神经退行性疾病和发育治疗的相关性，（6）神经毒性病毒蛋白和细胞间通讯，以及（7）神经成像和艾滋病。已为每个专题确定了全体会议发言人。这次会议是传播有关这些主题的新信息的有效手段，也是促进不同研究团队之间的调查和合作的新途径。会议还将为鼓励这一学科的初级调查人员提供一个有效的途径。伯杰博士作为会议组织者有着良好的记录。他是艾滋病神经科学会议的联合创始人和联合主席。在组织这次讲习班时，Berger博士和Pomerantz博士除了得到意大利神经艾滋病科学家当地组织委员会的协助外，还得到了艾滋病毒/艾滋病神经科学方面一批杰出的国际权威人士的协助。要求提供行政援助、全体会议发言人的旅费、受训人员奖学金和出版费用。拟议的会议是第一次强调艾滋病毒中枢神经系统和PNS疾病的神经保护。通过将这次会议与国际神经病毒学研讨会相结合，可以利用这种协同作用。

DESCRIPTION (provided by applicant): This application seeks support for the conference entitled HIV Neuroprotection Workshop to be held in conjunction with the 6th International Symposium on Neurovirology in Sardinia, Italy during September 10th- 14th, 2004. This conference is being held outside the U.S. The purpose of the conference is to bring together the world's experts in the pathophysiological mechanisms and clinical manifestations of the neurological, neuropsychological, and psychiatric complications of human immunodeficiency virus (HIV) infection. This conference will focus chiefly, but not exclusively, on the following: 1) clinical aspects of neurologic disease caused by HIV, (2) molecular and cellular aspects of HIV neuropathogenesis, (3) viral and cellular proteins in signal transduction and neuroprotection, (4) AIDS international roundtable, (5) Neuroimune interactions in AIDS: relevance to other neurodegenerative diseases and developmental therapeutics, (6) neurotoxic viral proteins and intercellular communications, and (7) neuroimaging and AIDS. Plenary speakers have been identified for each of these topics. This conference serves as efficient means to disseminate new information on these topics as well as to foster new avenues of investigation and collaborations between different research teams. The conference will also provide an effective avenue for encouraging junior investigators in this discipline. Dr. Berger has an established track record as a conference organizer. He is the co-founder and co-chair of the Neuroscience of HIV Meeting. In organizing this workshop, Drs. Berger and Pomerantz have the assistance of a distinguished group of international authorities on the neuroscience of HIV/AIDS in addition to the local organizing committee of Italian neuroAIDS scientists. Support is requested for administrative assistance, travel for plenary speakers, trainee scholarships, and publication costs. The proposed conference is the first of its kind to highlight neuroprotection in HIV CNS and PNS disorders. By coupling this meeting with the International Symposium on Neurovirology this synergy can be exploited.