Pediatric Interstitial Lung Disease Conference

小儿间质性肺疾病会议

• 批准号: 6838425
• 负责人: ROBIN R DETERDING
• 金额: $ 3万
• 依托单位: CHILDREN'S HOSPITAL OF DENVER
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-04-01 至 2005-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6838425
• 关键词: interstitial lung diseases; meeting /conference /symposium; pediatrics; travel

DESCRIPTION (provided by applicant): Pediatric interstitial lung disease (PILD) is a term used to describe a broad group of rare lung diseases. Infants and children with PILD have been shown to have significant morbidity and mortality depending upon the underlying etiology. Unfortunately, this field is complicated by confusion because of inconsistent classification systems, differences between children and adults with ILD, and poorly organized clinical networks to study and care for these patients. Yet, breakthroughs in basic science related to the identification of new disease causing genetic mutations and advances in molecular techniques provide powerful insights into important mechanisms for these diseases. These breakthroughs could provide novel life-changing treatment options for patients with PILD. We propose to change the paradigm in PILD by holding a groundbreaking conference. For the first time, a focused conference on PILD will bring together an outstanding multi-disciplinary group of individuals with clinical and basic science expertise. An innovative conference format will stimulate collaborative discussion on the current PILD state of the art, important emerging issues in the field, and relevant cutting edge scientific findings and techniques. To capitalize on the excitement and momentum generated by the conference, ideas will be further organized and harnessed in workshop working groups, focused on translating the best practices for investigating and caring for patients with PILD. We hope to create the foundation for a network of clinical care and research centers, develop the essential components of a clinical registry for specific types of PILD, clarify and organize the pathologic nomenclature specific to PILD, and identify initial key research questions. Communication between clinical and basic scientists and an enhanced interest in PILD will certainly occur. Ultimately the care of children with these rare diseases will be improved and the field advanced.

描述(由申请人提供)： 儿科间质性肺病(PILD)是一个用来描述一系列罕见肺部疾病的术语。根据潜在的病因，患有PILD的婴儿和儿童有显著的发病率和死亡率。不幸的是，由于分类系统不一致，儿童和成人ILD之间的差异，以及研究和护理这些患者的临床网络组织不善，这一领域因混乱而变得复杂。然而，与识别导致基因突变的新疾病相关的基础科学突破和分子技术的进步为这些疾病的重要机制提供了强有力的见解。这些突破可能为PILD患者提供改变生活的新治疗选择。 我们建议通过举办一次开创性的会议来改变PILD的范式。第一次，关于PILD的集中会议将聚集一个具有临床和基础科学专业知识的杰出的多学科个人小组。创新的会议形式将促进就当前PILD的最新技术、该领域的重要新兴问题以及相关的尖端科学发现和技术进行协作讨论。为了利用会议带来的兴奋和势头，将在研讨会工作组中进一步组织和利用想法，重点是转化调查和护理PILD患者的最佳实践。 我们希望为临床护理和研究中心网络奠定基础，为特定类型的PILD开发临床登记的基本组成部分，澄清和组织特定PILD的病理命名，并确定最初的关键研究问题。临床和基础科学家之间的交流和对PILD的兴趣增强肯定会发生。最终，对患有这些罕见疾病的儿童的护理将得到改善，这一领域将取得进展。