Assessment Of Ras And Renovascular Hypertension By Contr
Assessment Of Ras And Renovascular Hypertension By Contr
批准号:
6831371
负责人:
peter L choyke
金额:
$0.0万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
angiography artery stenosis bioimaging /biomedical imaging captopril clinical trial phase I diagnosis design /evaluation diagnosis quality /standard human subject inhalation drug administration kidney disorder diagnosis kidney imaging /visualization magnetic resonance imaging nuclear medicine oxygen compounds patient oriented research radiography renal hypertension renal ischemia /hypoxia
中文摘要
该方案的目的是确定磁共振血管成像(MRA)和卡托普利磁共振肾成像(MRI)是否可以对有肾血管性高血压风险的患者提供全面评估。虽然肾血管性高血压(肾动脉狭窄导致高血压)很少见,但它仍然代表了一种可纠正的高血压形式。目前评估肾血管性高血压患者的方法很繁琐,包括多普勒超声、卡托普利肾成像、MRA和血管造影术。该方案的目的是测试当前的金标准、卡托普利肾造影术和血管造影术与MRA和卡托普利MR肾造影术的组合。在这项研究中,高危患者接受了常规的卡托普利核医学肾图,然后是MR肾图和MRA。患者还呼吸一种名为Carbogen的富氧气体,这种气体用于检测肾脏缺血。到目前为止,我们已经招募了6名志愿者和16名患者参加该方案。我们预计,在未来的一年里,这种方案的患者将继续增加。
英文摘要
The purpose of this protocol is to determine whether magnetic resonance angiography (MRA) and captopril magnetic resonance renography (MRI) can provide comprehensive evaluation of patients at risk for renovascular hypertension. Although renovascular hypertension (renal artery stenosis causing high blood pressure) is unusual, it nonetheless represents a correctable form of hypertension. The current methods of evaluating patients for renovascular hypertension are cumbersome and include Doppler sonography, captopril renography, MRA and angiography. The purpose of this protocol is to test the current gold standards, captopril renography and angiography against a combination of MRA and captopril MR renography. For this study, the at-risk patient undergoes a conventional captopril nuclear medicine renogram followed by an MR renogram and MRA. The patient also breathes an oxygen-rich-gas known as carbogen which is used to test for renal ischemia. To date, we have accrued 6 volunteers and 16 patients to this protocol. We anticipate continued patient accrual to this protocol over the coming year.
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专著(0)
科研奖励(0)
会议论文
NMR Scanning on Patients
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批准号:6431767
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:peter L choyke
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依托单位:
Normal Volunteer Scanning On Magnetic Resonance
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批准号:6674037
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:peter L choyke
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依托单位:
Intracellular In vivo Imaging
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批准号:8763167
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项目类别:
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资助金额:$122.92万
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财政年份:--
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负责人:peter L choyke
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依托单位:
Instrumentation for microSPECT and microPET imaging
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批准号:8763170
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项目类别:
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资助金额:$61.46万
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财政年份:--
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负责人:peter L choyke
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依托单位:
Instrumentation for microSPECT and microPET imaging
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批准号:7291950
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:peter L choyke
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依托单位:
Prostate Cancer Imaging
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批准号:7291938
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:peter L choyke
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依托单位:
Growth Factor Imaging
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批准号:7291939
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:peter L choyke
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依托单位:
Instrumentation for microSPECT and microPET imaging
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批准号:7338752
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:peter L choyke
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依托单位:
Lymphatic Imaging
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批准号:8349088
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项目类别:
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资助金额:$33.18万
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财政年份:--
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负责人:peter L choyke
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依托单位:
Growth Factor Imaging
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批准号:8349090
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项目类别:
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资助金额:$199.07万
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财政年份:--
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负责人:peter L choyke
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依托单位:
Growth Factor Imaging and Photoimmunotherapy
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批准号:10702384
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项目类别:
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资助金额:$249.51万
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财政年份:--
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负责人:peter L choyke
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依托单位:
Cellular In vivo Imaging
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批准号:10014412
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项目类别:
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资助金额:$103.59万
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财政年份:--
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负责人:peter L choyke
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依托单位:
Instrumentation for microSPECT and microPET imaging
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批准号:10014415
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项目类别:
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资助金额:$34.53万
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财政年份:--
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负责人:peter L choyke
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依托单位:
Intracellular In vivo Imaging
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批准号:7592832
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项目类别:
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资助金额:$63.68万
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财政年份:--
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负责人:peter L choyke
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依托单位:
Angiogenesis imaging
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批准号:7965556
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项目类别:
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资助金额:$78.75万
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财政年份:--
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负责人:peter L choyke
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依托单位:
Lymphatic Imaging
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批准号:7733131
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项目类别:
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资助金额:$58.71万
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财政年份:--
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负责人:peter L choyke
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依托单位:
Instrumentation for microSPECT and microPET imaging
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批准号:10926051
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项目类别:
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资助金额:$197.32万
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财政年份:--
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负责人:peter L choyke
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依托单位:
Growth Factor Imaging and Photoimmunotherapy
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批准号:10926047
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项目类别:
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资助金额:$157.86万
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财政年份:--
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负责人:peter L choyke
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依托单位:
Cellular In vivo Imaging
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批准号:10926048
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项目类别:
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资助金额:$118.39万
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财政年份:--
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负责人:peter L choyke
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依托单位:
Intracellular In vivo Imaging
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批准号:8157385
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项目类别:
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资助金额:$83.71万
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财政年份:--
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负责人:peter L choyke
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依托单位:
海外基金