Assessment Of Ras And Renovascular Hypertension By Contr

本方案的目的是确定磁共振血管造影（MRA）和卡托普利磁共振肾成像（MRI）是否可以为肾血管性高血压风险患者提供综合评价。虽然肾血管性高血压（肾动脉狭窄导致高血压）是不常见的，但它仍然代表了一种可纠正的高血压形式。目前评价肾血管性高血压患者的方法是繁琐的，包括多普勒超声，卡托普利肾造影，MRA和血管造影。本方案的目的是测试当前的金标准，卡托普利肾造影和血管造影与MRA和卡托普利MR肾造影的组合。在这项研究中，高危患者接受常规的卡托普利核医学肾图检查，然后进行MR肾图和MRA检查。病人还呼吸一种被称为carbogen的富氧气体，用于检测肾缺血。到目前为止，我们已经招募了6名志愿者和16名患者参与本方案。我们预计在未来一年内，该方案将继续增加患者。

The purpose of this protocol is to determine whether magnetic resonance angiography (MRA) and captopril magnetic resonance renography (MRI) can provide comprehensive evaluation of patients at risk for renovascular hypertension. Although renovascular hypertension (renal artery stenosis causing high blood pressure) is unusual, it nonetheless represents a correctable form of hypertension. The current methods of evaluating patients for renovascular hypertension are cumbersome and include Doppler sonography, captopril renography, MRA and angiography. The purpose of this protocol is to test the current gold standards, captopril renography and angiography against a combination of MRA and captopril MR renography. For this study, the at-risk patient undergoes a conventional captopril nuclear medicine renogram followed by an MR renogram and MRA. The patient also breathes an oxygen-rich-gas known as carbogen which is used to test for renal ischemia. To date, we have accrued 6 volunteers and 16 patients to this protocol. We anticipate continued patient accrual to this protocol over the coming year.