Symposium on Retinal/ Choroidal Angiogenesis

描述（由申请人提供）：视网膜和脉络膜血管生成占发达国家所有失明的大多数。由于其深刻的经济和生活质量的影响，眼部血管生成是一个深入研究的过程，该领域正在以惊人的速度前进。因此，越来越难以管理来自对眼部和视网膜血管生成感兴趣的越来越多的研究者群体的信息。现在是进行评估的时候了，应该把重点放在集体研究的重要和可能有益的方面，并总结我们迄今为止的进展。即将举行的视网膜和脉络膜血管生成研讨会的主要目标是促进基础和临床科学家之间的当前信息和想法的交流，以促进我们对血管生成眼病的基本机制和治疗干预措施的发展的理解。已作出特别努力，鼓励新的研究人员参加，招募既有临床和基础科学背景的既定研究人员，并为两组提供充分的机会进行互动。我们在这一领域已经达到了一个点，在基础和临床科学家中，对理解这些视网膜疾病的基本机制有着强烈的共同兴趣。这次会议将负责促进合作研究项目，提供重要的新信息。研讨会将以丰富的研究人员为特色，从细胞和发育生物学家到来自美国主要研究/临床中心的临床科学家。会议将于2004年10月15日至16日在田纳西州纳什维尔举行。该计划将有8个平台会议，专门的海报展示时间和2个主题演讲。该计划已完成，包括视网膜和脉络膜血管生成的分子和细胞机制的基本信息，血管生成视网膜条件的体外和动物模型的详细描述，新的机制理论在人类疾病发病机制中的应用，以及治疗这些疾病的新治疗策略。主题演讲将由来自肿瘤血管生成领域的两名全国知名的研究人员发表。Kluwer Academic Publishers将以书籍的形式出版研讨会的会议记录，每位受邀演讲者贡献一章。唐纳德·M.加斯，医学博士同意写一篇介绍在这份申请中，我们要求资金支持20名年轻调查员和2名主旨发言人的差旅费和注册费。

DESCRIPTION (provided by applicant): Retinal and choroidal angiogenesis accounts for the majority of all blindness in developed countries. Because of its profound economic and quality-of-life impact, ocular angiogenesis is an intensely studied process and the field is advancing at an alarming pace. Thus, it is becoming increasingly difficult to manage the information coming from the growing group of investigators interested in ocular and retinal angiogenesis. It is time to take stock, to focus on the important and potentially beneficial aspects of the collective research, and to summarize our progress to date. The primary goal of the forthcoming Symposium on Retinal and Choroidal Angiogenesis is to promote the exchange of current information and ideas among basic and clinical scientists in order to foster advances in our understanding of basic mechanisms and development of therapeutic interventions for angiogenic eye conditions. Special effort has been made to encourage new investigators to attend, to recruit established investigators with both clinical and basic science backgrounds, and to provide ample opportunity for the two groups to interact. We have reached a point in this field where there is strong common interest among basic and clinical scientists in understanding the fundamental mechanisms underlying these retinal conditions. This meeting will be responsible for fostering collaborative research projects that will provide vital new information. The symposium will feature a rich mixture of investigators, ranging from cell and developmental biologists to clinician-scientists from major research/clinical centers throughout the U.S. The meeting will be held in Nashville, TN on October 15 - 16, 2004. The program will have 8 platform sessions, dedicated time for poster presentations, and 2 keynote lectures. The program is finalized and includes basic information on molecular and cellular mechanisms of retinal and choroidal angiogenesis, detailed descriptions of in vitro and animal models of angiogenic retinal conditions, applications of new mechanistic theories to human disease pathogenesis, and novel therapeutic strategies for treatment of these conditions. The keynote lectures will be delivered by two nationally known investigators from the field of tumor angiogenesis. Kluwer Academic Publishers will publish the proceedings of the symposium in the form of a book, with each invited speaker contributing a chapter. J. Donald M. Gass, M.D. has agreed to write an introduction. In this application we request funds to support travel and registration costs of 20 young investigators and 2 keynote speakers.