Conference on Translational Medicine in Autoimmunity

描述(申请人提供)：在了解自身免疫性疾病的基本机制方面的最新进展导致了试剂的开发，这些试剂可能会干扰疾病的进程并限制疾病的进展。虽然免疫介导性疗法已经被证明对特定的自身免疫性疾病有效，但临床免疫学的最新进展将导致治疗自身免疫性疾病的新方法。这些新型药物在治疗人类疾病方面的应用正在扩大。临床和基础科学家必须熟悉这些治疗难治性疾病的新方法。本次会议将集中讨论这些治疗药物治疗和管理几种自身免疫性疾病的机制和应用，这些疾病包括多发性硬化症、炎症性肠病、糖尿病、系统性红斑狼疮和类风湿性关节炎。会议的主要重点将是为观众提供信息，以更好地欣赏最新技术及其对床边医学的转化。为此，这次会议的主要目标受众将是临床医生、转化研究科学家、博士后研究员和对收集更多该领域当前研究活动知识感兴趣的研究生。这次会议代表着Keystone研讨会的一个重要新方向。它响应了最近制定的“NIH路线图”，该路线图将转化医学作为这一路线图的关键道路。Keystone研讨会与免疫学前沿的历史性联系将使我们能够将基础和临床科学家引入这个新论坛。

DESCRIPTION (provided by applicant): Recent advances in the understanding of basic mechanisms of autoimmune disease have led to the development of reagents that can potentially interfere with the disease process and limit disease progression. Although immune mediated therapeutics have already been proven effective for selected autoimmune conditions there are recent developments in clinical immunology that will lead to new approaches for the treatment of autoimmune disease. The implementation of these novel agents into treating human disease is expanding. It is essential that clinical and basic scientists become familiar with these novel approaches for the treatment of these refractory conditions. This meeting will focus on the mechanism and utilization of these therapeutics for the treatment and management of several autoimmune diseases including multiple sclerosis, inflammatory bowel disease, diabetes, systemic lupus and rheumatoid arthritis. The primary emphasis for the sessions will be to provide the audience with information to better appreciate the state of the art and its translation to bedside medicine. To this end, the prime target audience for this meeting will be clinical physicians, translational research scientists, post-doctoral fellows and graduate students interested in gathering more knowledge of the current investigational activities in the field. This meeting represents an important new direction for the Keystone Symposia. It is responsive to the recently formulated "NIH Roadmap" that has targeted translational medicine as a key roadway of this map. The historic association of the Keystone Symposia with frontiers in immunology will allow us to bring in both basic and clinical scientists to this new forum.