2004 Microbial Stress Response Gordon Conference

描述(由申请人提供)：本提案请求部分支持将于2004年7月11日至7月16日在Mt.霍利奥克学院。这次非常成功的会议是唯一一次广泛地考虑原核生物中所有应激表现形式的会议，包括特定的应激反应、发育和发病机制。会议还考虑了真核微生物中的相关应激反应。这次会议的优势在于，它汇集了来自相关但往往不交叉的领域的尖端研究，以便进行思想的交叉培养。会议的拟议会议是：I--氧化胁迫，II--寄主病原体的相互作用；III--原核发育；IV--感受和调节胁迫的小RNA；V--胁迫和发育中的蛋白质分解；VI--信号的计算和基因组方法；VII--微生物生态/多样性；VIII--胁迫反应基因表达中的信号转导途径；IX--敏感的生长阶段。目前的会议包括对金属在应激反应中的相当大的讨论，并扩大了对基因组分析和建模的重视。通过将计算科学家和实验者聚集在一起，我们希望在这一不断扩大的领域中实现未来的合作。作为本次会议威望的一个指标，我们注意到，会议主席包括原核生物生物学领域的许多重要人物。每堂课将有几位特邀演讲者和一些从摘要中挑选出来的演讲者。我们今年的演讲者包括女性、少数族裔和新教职员工。参与者通常包括：主要在主要研究机构的新老教师，但也有相当大一部分来自小型文理学院的教师、工业科学家、博士后研究员和学生。这次会议的认购额普遍超额，鉴于目前的计划可能会有非常广泛的吸引力。

DESCRIPTION (provided by applicant): This proposal requests partial support for a Gordon Research Conference on The Microbial Stress Response to be held from July 11 to July 16, 2004 at Mt. Holyoke College. This extraordinarily successful meeting is the only one that broadly considers all manifestations of stress in prokaryotic organisms, including specific stress responses, development and pathogenesis. The meeting also considers relevant stress responses in eukaryotic microbes. The strength of this meeting is that it brings together cutting edge research from related but often non-intersecting fields to allow cross-fertilization of ideas. The proposed sessions for the meeting are: I--Oxidant stresses, II--The Host pathogen interaction; III--Prokaryotic development; IV--Small RNAs in sensing and regulating stress; V--Proteolysis in stress and development; Vl--Computational and genomic approaches to signaling; VII--Microbial ecology/diversity; VIII--Signal transduction pathways in stress responsive gene expression; IX--Sensing growth stages. The current meeting includes a sizeable discussion of metals in stress responses and features an expanded emphasis on genomic analysis and modeling. By bringing together computational scientists with experimentalists, we expect to nucleate future collaborations in this expanding area. As one indicator of the prestige of this meeting, we note that session chairs include many of the major figures in prokaryotic biology. Each session will have several invited speakers and some speakers chosen from the abstracts. Our speakers this year include women, minorities and new faculty. Participants generally include: new and established faculty mostly at major research institutions, but with a sizeable representation of those from small liberal arts colleges, scientists in industry, postdoctoral fellows, and students. This meeting is generally oversubscribed and given the current program is likely to have very wide appeal.