Bacterial Cell Surfaces Gordon Conference

描述（由申请人提供）：本提案适用于支持第16届细菌细胞表面戈登会议，将于6月27日至7月2日在科尔比索耶学院在新伦敦，新罕布什尔州举行。本次会议的传统重点是细菌膜的结构和功能，包括发病机制，抗生素耐药性和膜转运等主题，这些仍然是下一次会议的中心主题。借助高分辨率的膜蛋白，如AcrB多药外排转运蛋白，BtuCD ABC ATP酶，紫胶通透酶，电压门控钾通道和GIPF aquaglyceroporin的结构数据，2004年会议将成为一个主要的平台，讨论获得的机制信息的膜蛋白。此外，这次会议将扩大到生物恐怖主义和抗生素耐药性领域，2004年将介绍毒素、噬菌体裂解酶的功能、结构和调节，并详细讨论β-内酰胺酶。因此，拟议的会议应实现介绍分子微生物学领域最前沿研究的目标。 在细菌细胞表面戈登会议的参与者包括在这一领域的领导者，从学术界，政府和行业，以及更多的初级科学家，包括许多研究生和博士后研究员谁代表这一领域的未来绘制。在当前应用程序中寻求的支持的主要用途是帮助这些初级人员参加这个会议。戈登会议的组织是为了最大限度地利用讨论和介绍这一领域最新研究结果的机会，每天下午都有海报会议，每次正式会议之后都有讨论时间。

DESCRIPTION (provided by applicant): This proposal applies for support for the 16th Bacterial Cell Surfaces Gordon Conference, to be held from June 27 to July 2 at Colby-Sawyer College in New London, New Hampshire. The traditional focus of this meeting is on the structure and function of bacterial membranes, including such topics as pathogenesis, antibiotic resistance and membrane transport, and these continue to be central themes in the next conference. Aided by high-resolution structural data on membrane proteins such as the AcrB multidrug efflux transporter, the BtuCD ABC ATPase, the Lac permease, the voltage-gated potassium channel and the GIpF aquaglyceroporin, the 2004 Conference will become a major platform for the discussion of mechanistic information obtained on integral membrane proteins. In addition, this meeting will expanded into the areas of bioterrorism and antibiotic resistance, with presentations in 2004 on the function, structure and regulation of toxins, phage lytic enzymes, and detailed discussions of beta-Iactamases. The proposed meeting should thus accomplish the goal of presenting the cutting-edge research in the area of molecular microbiology. The participants at the Bacterial Cell Surfaces Gordon Conference include the leaders in this field, drawn from academics, government and industry, as well as more junior scientists, including many graduate students and postdoctoral fellows who represent the future of this area. A major use of the support sought in the current application is to assist such junior people in participating in this meeting. The Gordon Conference is organized to maximize the opportunity for discussion and for the presentation of the latest findings in this area, with poster sessions occurring every afternoon and discussion periods after each formal session.