Eighth International Workshop on Radiation Damage to DNA

简介（由申请人提供）：“辐射对DNA的损伤”国际研讨会将涵盖辐射能量在DNA中沉积引发的途径的最新进展，通过DNA的化学和生化变化，直至DNA损伤的最终生物学后果。这是放射物理学家、化学家和生物学家以高度互动、多学科的形式讨论辐射对DNA的损害的一系列研讨会中的第八次。研讨会将于2004年5月25日至30日在加拿大班夫的班夫会议中心举行。参加人数限制为105人。参与者将来自世界各地的学术和研究机构，包括研究生、博士后、职业中期和高级科学家。

DESCRIPTION (provided by applicant): The International Workshop on "Radiation Damage to DNA" will cover recent advances in the understanding of the pathways initiated by radiation energy deposition in DNA through the chemical and biochemical changes in the DNA to the ultimate biological consequences of the DNA lesions. This the eighth in a series of workshops that bring together radiation physicists, chemists and biologists to discuss radiation damage to DNA in a highly interactive, multidisciplinary format. The workshop will be held May 25-30, 2004 at the Banff Conference Centre in Banff, Canada. The number of participants is limited to 105. The participants will be from academic and research institutions world-wide and will include graduate students, post-doctoral fellows, and mid-career and senior scientists. The topics that will be covered at the meeting include transient DNA radicals, identification and measurement of base/nucleoside end products in irradiated DNA, track structure, clustered damage, charge/energy transfer in DNA, high LET effects, reactions of low energy radiations, role of chromatin structure in DNA damage induction and repair, radiolytic footprinting, structure of damaged DNA bases and the proteins that recognize them, repair of DNA base damage, radiation-induced strand break termini, repair of DNA double strand breaks, mutation induction, and other biological consequences of unrepaired DNA damage. An important goal of this meeting is to decrease polarization by discipline and stimulate new, interdisciplinary thinking and experimental approaches by scientists who become aware of the relevance of findings from other fields to their own work. Although the focus spans physics, chemistry and biology, the common goal of all the participants is to increase understanding of the biological endpoints in terms of predictable physical events and chemical alterations that occur in irradiated DNA. To this end, a strong effort will be made to work on a common language between all the disciplines, with the objective of facilitating communications and research interactions among individuals in the various research areas.