Reducing Behavior Risks for Causing New HIV Infections

减少导致新的艾滋病毒感染的行为风险

• 批准号: 6896876
• 负责人: ROSEMARY RYAN
• 金额: $ 30.83万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-07-01 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6896876
• 关键词: AIDS education /prevention; HIV infections; behavior prediction; behavior therapy; behavioral /social science research tag; bisexual; health care service utilization; high risk behavior /lifestyle; homosexuals; human subject; human therapy evaluation; interview; motivation; patient oriented research; safe sex /sex abstinence; sex behavior; sex partner

Despite early gains in sexual safety among gay and bisexual men, recent increases in other STDs indicate that new HIV infections are probably on the rise in this population. HIV+ MSM continue to have unprotected anal sex, often with partners to whom they have not disclosed their serostatus. Historically, intervention efforts have focused primarily on HIV negative persons. As attention shifts to prevention programming for HIV+ individuals, there is evidence to suggest that new acceptable and effective models for engaging and delivering prevention services to HIV+ individuals are needed. We have pilot tested a promising two-session behavior assessment and Motivational Interviewing feedback intervention with sexually active, HIV+ MSM. Among 114 men who completed a 6 month follow-up interview, the proportion of those reporting unprotected anal intercourse with partners whose HIV serostatus was negative or unknown to them fell by 40 percent, from 44 percent at baseline to 26 percent at follow-up. With this proposal, we are seeking support to test the intervention in a controlled trial setting, comparing men randomly assigned to a Motivational Enhancement Interviewing (ME) sexual behavior assessment/feedback intervention with those assigned to a non-ME assessment/discussion condition exploring care service needs and utilization. We will assess effectiveness and durability of change at 4 and 12 months post intervention.

尽管同性恋和双性恋男性在性安全方面取得了初步进展，但最近其他性传播疾病的增加表明，这一人群中新的艾滋病毒感染可能正在上升。HIV+MSM继续进行无保护的肛交，通常是与他们没有透露血清状况的伴侣发生性行为。从历史上看，干预工作主要集中在艾滋病毒阴性者身上。随着注意力转向艾滋病毒感染者的预防方案，有证据表明，需要新的可接受和有效的模式，让艾滋病毒感染者参与并向艾滋病毒感染者提供预防服务。我们已经对性行为活跃的HIV+MSM进行了有前景的两次行为评估和激励性访谈反馈干预的试点测试。在114名完成了6个月随访采访的男性中，报告与艾滋病毒血清抗体阴性或未知的伴侣发生无保护肛交的比例下降了40%，从基线的44%下降到随访时的26%。通过这项建议，我们正在寻求支持，以在受控试验环境中测试干预措施，将随机分配到动机增强访谈(ME)性行为评估/反馈干预的男性与被分配到非ME评估/讨论条件的男性进行比较，以探索护理服务的需求和利用。我们将在干预后4个月和12个月评估变化的有效性和持久性。