Core--Viral vector

载体核心的目的是为正在进行的研究提供打包的病毒载体，作为代谢紊乱基因治疗计划的一部分。重组DNA操作将在个别研究人员的实验室进行，以产生特定的载体结构。然后将这些载体构建物包装在载体核心中，依靠载体核心实验室在这些制备过程中的丰富经验。为该计划准备的载体类型包括重组

The purpose of the Vector Core is to provide packaged virus vectors for investigations being carried out as a part of the Gene Therapy for Metabolic Disorders program. Recombinant DNA manipulations will be carried out in the laboratories of the individual investigators to generate specific vector constructs. These vector constructs will then be packaged in the Vector Core, relying on extensive experience of the vector core laboratory in the procedures carried out for these preparations. Vector types to be prepared for this program include recombinant lentivirus vectors, adeno-associated virus vectors, and adenovirus vectors for Projects I, II and IV, respectively. The Vector Core will also provide guidance on vector construct design and analysis for vector-mediated gene transfer into target cell populations.