Exploring and exploiting novel therapeutic avenues in mesothelioma

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Mesothelioma is a fatal cancer of the lungs. It rapidly grows and invades surrounding tissues such as the ribcage, causing severe shortness of breath and pain. Chemotherapy has limited effect and although immunotherapy appears promising, most patients do not respond. I will investigate why mesothelioma is so invasive; how to improve the response to immunotherapy and how to best combine chemotherapy and immunotherapy. I aim to develop new treatments that will benefit patients with mesothelioma.