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Exploring and exploiting novel therapeutic avenues in mesothelioma

Exploring and exploiting novel therapeutic avenues in mesothelioma
探索和开发间皮瘤的新治疗途径
批准号:
nhmrc : 1126076
负责人:
金额:
$29.04万
依托单位国家:
澳大利亚
项目类别:
Career Development Fellowships
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 2020-12-31

项目摘要

项目成果

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中文摘要
翻译
间皮瘤是一种致命的肺癌。它迅速生长并侵入周围组织,如胸腔,导致严重的呼吸急促和疼痛。化疗效果有限,尽管免疫疗法似乎很有希望,但大多数患者没有反应。我将研究为什么间皮瘤是如此具有侵袭性;如何提高免疫治疗的反应,以及如何最好地联合收割机化疗和免疫治疗。我的目标是开发新的治疗方法,这将有利于间皮瘤患者。
英文摘要
Mesothelioma is a fatal cancer of the lungs. It rapidly grows and invades surrounding tissues such as the ribcage, causing severe shortness of breath and pain. Chemotherapy has limited effect and although immunotherapy appears promising, most patients do not respond. I will investigate why mesothelioma is so invasive; how to improve the response to immunotherapy and how to best combine chemotherapy and immunotherapy. I aim to develop new treatments that will benefit patients with mesothelioma.
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