Building Interdisciplinary Research Careers in Women's Health (BIRCWH) Center

描述(申请人提供)：BIRCWH中心的总体主题是强调对妇女疾病的基本方法，包括发育生物学、分子遗传学和细胞生物学、行为科学、心血管科学、获得性免疫缺陷疾病、衰老及其影响妇女的问题，以及翻译和临床调查研究。所有拟议的教师导师都将能够提供培训，允许BIRCWH学者建立自己的独立、可资助的研究计划，适用于女性的临床问题。 目前我们有三位学者，分别来自泌尿外科、内科(风湿病学)和妇产科。三人都是女性，一人是波多黎各人。他们都获得了同行评审的联邦拨款；一个是R-01，一个是退伍军人职业发展奖，还有一个是R-21。所有这一切都是可能的，因为他们能够在获得BIRCWH赠款支持的同时生成初步数据。我们的一位毕业学者是一位非裔美国人，他获得了NIH K-01奖，目前是医学系(心脏病学)的助理教授。 BIRCWH中心的影响已经超出了新项目发展奖获得者的范围，并促进了与妇女健康相关的研究的启动和跨部门教职员工之间的合作，并促进了招募医学生、内部官员和研究员参与与妇女健康相关的基础和临床研究。鉴于已经建立的BIRCWH中心的活动采用多学科方法，而且我们机构是妇女生殖健康研究事业发展中心的国家级站点之一，并且被妇女健康/公共卫生服务办公室授予国家英才中心合同，因此为今后创建一个“妇女健康研究中心”奠定了基础，该中心涵盖与妇女健康相关的研究、培训和教学。BIRCWH和WRHR中心的建立也帮助了我们附属的少数民族机构--King/Drew医学院。例如，加州大学洛杉矶分校的金/德鲁医学院和大卫·格芬医学院申请并获得了题为“德鲁-加州大学洛杉矶分校生殖科学研究中心：雄激素对男性和女性的生物影响”的赠款。 BIRCWH的赠款将帮助培训来自不同学科的科学家从事妇女健康方面的研究，妇女健康是公共卫生中一个服务不足的领域。

DESCRIPTION (provided by applicant): The overall theme of the BIRCWH Center has been to emphasize a fundamental approach to the diseases of women that include the disciplines of developmental biology, molecular genetics and cell biology, behavioral science, cardiovascular science, acquired immune deficiency disease, aging and its problems as it affects women, as well as translational and clinical investigative research. All of the proposed faculty mentors will be able to provide training to allow the BIRCWH Scholars to establish their own independent, fundable research programs applicable to the clinical problems of women. At present we have three Scholars; from Urology, Medicine (Rheumatology), and Obstetrics and Gynecology. All three are women, and one a Puerto Rican. All of them have been awarded peer-reviewed federal grants; one an R-01, one a VA Career Development Award, and one an R-21. All of this was possible because they were able to generate preliminary data while receiving BIRCWH grant support. One of our Scholars who graduated is an African-American who obtained an NIH K-01 award and is at present an Assistant Professor in the Department of Medicine (Cardiology). The impact of the BIRCWH Center has already extended beyond the New Program Development Awardees and has stimulated initiation and collaboration of research related to Women's Health between various faculty members transcending departmental boundaries and facilitated the recruitment of medical students, house officers, and fellows into investigative basic and clinical research related to Women's Health. In view of the multidisciplinary approach of the activities of the already established BIRCWH Center, and the fact that our institution is one of the national sites for the Women's Reproductive Health Research Career Development Center, as well as being awarded the National Center of Excellence Contract by the Office of Women's Health/Public Health Service, the foundations have been laid for the future creation of a "Women's Health Research Center" encompassing research, training, and teaching in matters related to Women's Health. The establishment of the BIRCWH and WRHR Centers has also helped our affiliated minority institution; the King/Drew Medical School. For example, the King/Drew Medical School and the David Geffen School of Medicine at UCLA applied for and received a grant entitled "Drew-UCLA Reproductive Sciences Research Center: Biologic Effects of Androgens in Men and Women". The BIRCWH grant will help train scientist from various disciplines to do research in Women's Health, which is an underserved area in public health.