Exploring the role of the Bcl-2 family in haematopoiesis and haematopoietic malignancy

探索 Bcl-2 家族在造血和造血系统恶性肿瘤中的作用

• 批准号: nhmrc : 1090500
• 负责人: Dr Kylie Mason
• 金额: $ 12.73万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/exploring-role-bcl-haematopoietic-malignancy/519288
• 关键词: Exploring; role; Bcl; family; haematopoiesis

Chronic Lymphocytic Leukaemia and Non-Hodgkin Lymphoma comprise the majority of blood cancers and are both disease in which the cell death pathway plays a vital role in both the development of the cancer cell and the resistance to chemotherapy. This project aims to examine the mechanisms of cancer in these tumours focussing on lymphoid cancers, and examine the role of new treatments targeting this pathway.

慢性淋巴细胞性白血病和非霍奇金淋巴瘤是血癌的主要类型，在这两种疾病中，细胞死亡途径在癌细胞的发展和对化疗的抵抗中都起着至关重要的作用。这个项目的目的是研究这些肿瘤中的癌症机制，重点是淋巴癌，并检查针对这一途径的新疗法的作用。