A randomized, double-blinded controlled trial (RCT) of a new whole IgG, equine antivenom compared to the currently used F(ab’)2 CSL taipan antivenom, for the treatment of Papuan taipan (Oxyuranus scutellatus) envenoming in Papua New Guinea.

一项随机、双盲对照试验 (RCT)，将新型全 IgG 马抗蛇毒血清与目前使用的 F(abâ)2 CSL 太攀蛇抗蛇毒血清进行比较，用于治疗巴布亚新几内亚的巴布亚太攀蛇 (Oxyuranus scutellatus) 中毒

• 批准号: nhmrc : 1033977
• 负责人: Dr David Williams
• 金额: $ 96.89万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/randomized-double-blinded-new-guinea/110906
• 关键词: randomized; double; blinded; controlled; trial

Snakebite is very common in Papua New Guinea (PNG), and many bites are caused by the Papuan taipan, a highly venomous snake found in the southern PNG savannah's. Current antivenom is expensive (US$1500) and many patients do not receive optimal treatment. We will conduct a randomised controlled trial of a new, low cost taipan antivenom developed specifically for PNG. The safety and efficacy of the new antivenom is compared to the existing product to determine if it is a suitable alternative.

蛇咬伤在巴布亚新几内亚(PNG)非常常见，许多咬伤是由巴布亚大班蛇引起的，巴布亚大班是一种在巴布亚新几内亚大草原南部发现的剧毒蛇。目前的抗蛇毒血清价格昂贵(1500美元)，许多患者没有得到最佳治疗。我们将对专门为PNG开发的一种新的低成本大班抗蛇毒血清进行随机对照试验。将新抗蛇毒血清的安全性和有效性与现有产品进行比较，以确定它是否是合适的替代品。