Taining Program in Cadiovascular Biology and Medicine

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EXCEED THE SPACE PROVIDED. This is an exciting and dynamic time in which molecular biology and genomic technologies have transformed cardiovascular research. The primary purpose of this training grant is to provide rigorous research training for cardiology fellows and PhD scientists in cardiovascular biology and medicine with the ultimate goal of preparing trainees as independent clinician-scientists and investigators. The specific rationale underlying the training program is that state-of-the-art cardiovascular research (basic, translational and patient-oriented) requires a strong foundation in molecular and cellular biology. For example, trainees in the Genetics and Genomics of Heart Failure Program will take graduate courses in Human Genetics and bio-informatics, which is then applied to understanding the genetic basis of cardiomyopathy. Dr. Michael Parmacek, the former Co- P.I. and Chief of the Division of Cardiovascular Medicine, will serve as the Program Director. Professor H. Lee Sweeney, Chairman of Physiology, will serve as Co-P.I. of the training program. Together, they will coordinate a multi-disciplinary group of training faculty that include well-funded and established investigators from the Departments of Medicine, Physiology, Pharmacology, Cell and Developmental Biology, Genetics, the Institute for Medicine and Engineering and the Center for Clinical Epidemiology and Biostatistics. Pre- and postdoctoral Trainees for this program will be selected from the Perm Cardiology Fellowship Training program, the Perm Combined Degree Program (MD/PhD) and the Biomedical Graduate Studies (BGS) program. In addition, a strategy to attract individuals from under-represented minorities has been implemented. Trainees will have full access to the newly established University of Pennsylvania Molecular Cardiology Center and Laboratories for Experimental Electrophysiology and Interventional Cardiology. The core training will be a well-supervised research preceptorship lasting a minimum of two years. This training will be supplemented by graduate school classes, lectures, seminars, and specific courses in the ethical conduct of research. The training program has implemented a formal mentoring program and established an Oversight Committee to monitor trainee progress. The inter-departmental structure of this training program provides potential for an unparalleled training environment in cardiovascular research. PERFORMANCE SITE ========================================Section End===========================================