Conference--Prouts Neck Prostate Cancer

描述(由申请人提供)： 鉴于前列腺癌的高发病率和高死亡率只会随着美国人口老龄化而增加(到2020年，60岁以上的男性数量将增加两倍)，召开这种性质的会议是极其重要和及时的。受邀的年轻科学家在前列腺癌研究领域相对较新，他们将在这次会议上发挥核心作用。虽然还会有其他关于前列腺癌的会议，但这次会议的方法和主题都是及时和独特的。这是一项关于前列腺癌的三次Prouts Neck系列会议的会议赠款资金申请，该会议将在缅因州Prouts Neck的Black Point Inn举行。请提供支助，每年举行一系列三次会议，第一次于2002年11月7日至10日举行，随后于2004年和2006年举行。关于前列腺癌的普鲁茨颈部会议因其在确定治疗、预防和控制前列腺癌的基础研究方法方面的总体卓越而享誉国际。这将是第9次Prouts Neck会议，并将遵循成功证明的形式，召集主要权威和新的调查人员，他们将解决当今前列腺癌领域最具挑战性的、尚未解决的问题。第一次会议的主题是前列腺癌发生的早期事件--干预策略和标记物的机会，随后将于2004年举行一次会议，重点讨论晚期前列腺癌--一种多学科方法，并于2006年重点讨论前列腺癌的治疗。本申请中提出的会议的主要目标之一是让该领域的高级研究人员提出他们认为下一代前列腺癌研究人员要解决的最重要的基础和临床研究挑战。因此，将青年调查员纳入本次会议是高度优先的。基础和临床研究人员将有机会在正式和非正式的环境中交流新的数据、技术和想法。会议将以概述讲座开始，这些讲座将给年轻的研究人员带来研究挑战。随后的五场会议将由高级研究人员的概述讲座、青年研究人员的讲台陈述、问答时间和小组讨论开始，重点讨论前列腺癌的分子发病机制、遗传和环境对前列腺癌发展的影响、前列腺癌预防的新机会和前列腺癌诊断和检测的新策略。会议的目标将是： (1)明确前列腺癌研究的挑战和机遇；(2)通过确定高度优先的、尚未解决的基础和临床问题并讨论研究方法，鼓励年轻和成熟的研究人员将他们的研究努力集中在前列腺癌上；(3)鼓励对与前列腺癌的生物学、预防和管理相关的现有数据进行多学科分析；(4)确定开发前列腺癌新的预防、诊断和治疗方法所需的研究机会、方法和资源；(5)促进研究和鼓励合作研究，将不同的专业知识和资源集中在与前列腺癌相关的优先主题上；(六)在有关刊物上发表会议纪要。

DESCRIPTION (provided by applicant): Given the high incidence and mortality of prostate cancer which will only increase with the aging of the American population (the number of men over the age of 60 will triple by the year 2020), a meeting of this nature is extremely important and timely. Invited young scientists who are relatively new to the field of prostate cancer research will play central roles in this meeting. While there will be other meetings on prostate cancer, the approach and theme for this conference are both timely and unique. This is a request for conference grant funding of a series of three Prouts Neck Meetings on Prostate Cancer which will be at the Black Point Inn in Prouts Neck, Maine. Support is requested that a series of three meetings which will be held every year beginning with the first on November 7-10, 2002 and the subsequent meetings held in 2004 and 2006. The Prouts Neck Meetings on Prostate Cancer have become internationally renowned for their overall excellence in terms of defining basic research approaches to the treatment, prevention and control of this disease. This will be the 9th Prouts Neck Meeting and will follow the successfully proven format of assembling leading authorities and new investigators who will address today's most challenging, unresolved, problems in the field of prostate cancer. The topic for the first meeting is Early Events in Prostate Carcinogenesis - Opportunities for intervention Strategies and Markers and will be followed in 2004 with a meeting focused on Late Stage Prostate Cancer - A Multidisciplinary Approach and in 2006 with a focus on Treatment of Prostate Cancer. One of the principal objectives of the meeting proposed in this application is to have senior investigators in the field present what they perceive to be the most important basic and clinical research challenges for the next generation of prostate cancer researchers to address. Accordingly, high priority is placed on the inclusion of young investigators in this meeting. Basic and clinical investigators will be afforded the opportunity to exchange new data, technology and ideas in both formal and informal settings. The conference will begin with overview lectures which will pose research challenges to the young investigators. Five ensuing sessions emphasizing the molecular pathogenesis of prostate cancer, genetic and environmental influences on prostate cancer development and new opportunities for prostate cancer prevention and new strategies for prostate cancer diagnosis and detection will be led off by overview lectures for senior investigators, followed by podium presentation by young investigators, question/answer periods and panel discussions. The goals of the conference will be to: (1) to define the challenges and opportunities for prostate cancer research; (2) to encourage young and established investigators to focus their research endeavors on prostate cancer by defining high priority, unresolved basic and clinical issues and discussing approaches of investigation; (3) encourage multidisciplinary analysis of current data relevant to the biology, prevention and management of prostate cancer, (4) to identify research opportunities, approaches and resources needed to develop new preventative, diagnostic and treatment approaches for prostate cancer; (5) to promote research and encourage collaborative studies which will focus diversified expertise and resources on priority topics relevant to prostate cancer; and (6) to publish a summary of the conference in an appropriate journal.