Core--Radiation resource

核心--辐射资源

• 批准号: 7055186
• 负责人: JEFFREY L. SCHWARTZ
• 金额: $ 21.49万
• 依托单位: FRED HUTCHINSON CANCER RESEARCH CENTER
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-01 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7055186
• 关键词: alpha radiation; biomedical facility; gamma radiation; radiation dosage; radiobiology

The overall objectives of the program are to develop biodosimetry and effective countermeasures for radiation exposure. All projects will require access to different radiation sources. The Radiation Resource Core will provide dosimetry, radiobiology support, as well as access to different types of radiation sources including both low and high LET radiations. The Core will be responsible for advising on appropriate radiation sources to use and will coordinate irradiation protocols. The Core will directly supervise any gamma-ray exposures that use the J.L. Shepherd Model 81-14A Cs-137 irradiator. This irradiator has the capability of providing both whole body and partial body exposures of small animals. The Core will also oversee the irradiations with the Varian CLINAC 4 at the Fred Hutchinson Cancer Research Center and will provide access to alpha radiation. The alpha source will, be At-211, which is generated in the medical cyclotron in the Department of Radiation Oncology at the University of Washington.

该方案的总体目标是发展生物剂量学和有效的辐射照射对策。所有项目都需要接触不同的辐射源。辐射资源核心将提供剂量测定、放射生物学支持，以及获得不同类型的辐射源，包括低和高LET辐射。核心将负责建议使用适当的辐射源，并协调辐照方案。核心将直接监督使用J.L. Shepherd 81- 14 A型Cs-137辐照器。该辐照器能够提供小动物的全身和局部暴露。核心还将在弗雷德哈钦森癌症研究中心与瓦里安公司的CAAC 4一起监督辐照，并将 提供了接触阿尔法辐射的途径α源将是At-211，其在华盛顿大学放射肿瘤学系的医用回旋加速器中产生。