Core--Radiation resource

核心--辐射资源

• 批准号: 7055186
• 负责人: JEFFREY L. SCHWARTZ
• 金额: $ 21.49万
• 依托单位: FRED HUTCHINSON CANCER RESEARCH CENTER
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-01 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7055186
• 关键词: alpha radiation; biomedical facility; gamma radiation; radiation dosage; radiobiology

The overall objectives of the program are to develop biodosimetry and effective countermeasures for radiation exposure. All projects will require access to different radiation sources. The Radiation Resource Core will provide dosimetry, radiobiology support, as well as access to different types of radiation sources including both low and high LET radiations. The Core will be responsible for advising on appropriate radiation sources to use and will coordinate irradiation protocols. The Core will directly supervise any gamma-ray exposures that use the J.L. Shepherd Model 81-14A Cs-137 irradiator. This irradiator has the capability of providing both whole body and partial body exposures of small animals. The Core will also oversee the irradiations with the Varian CLINAC 4 at the Fred Hutchinson Cancer Research Center and will provide access to alpha radiation. The alpha source will, be At-211, which is generated in the medical cyclotron in the Department of Radiation Oncology at the University of Washington.

该计划的总体目标是开发辐射暴露的生物剂量学和有效的对策。所有项目都需要获得不同的放射源。辐射资源核心将提供剂量测定、放射生物学支持，以及获得不同类型的放射源，包括低LET和高LET辐射。核心将负责就要使用的适当放射源提供建议，并将协调辐照方案。该核心将直接监督任何使用J.L.谢泼德81-14ACs-137型辐照器的伽马射线曝光。这种照射器具有提供小动物全身和局部照射的能力。核心还将监督弗雷德·哈钦森癌症研究中心的瓦里安CLINAC 4的照射情况，并将 提供获得阿尔法辐射的途径。阿尔法源将在-211，这是由华盛顿大学放射肿瘤学系的医学回旋加速器产生的。