How alphaviruses cause disease and identifying new therapeutics.

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Alphaviruses are transmitted by mosquitoes and cause a variety of serious human infections. This project investigates how alphaviruses cause disease, with special focus on inflammatory musculoskeletal diseases. The expected outcomes are a better understanding of human viral diseases, with a view to improving prevention and treatment strategies to reduce the disease burden of alphaviruses and related viruses. The research strategy is a world-first, and the institute is an international leader in this area.