Improved Safe Alternative to Semiconductor Quantum Dots

描述(申请人提供)：量子点被公认为用于生物标记应用的新一代发光试剂的核心材料。该项目将为一类新的无毒、不含金属的量子点状材料建立概念验证。我们将合成这些新材料，对它们进行水溶性衍生化，并表征它们的组成和发射性能。这些材料具有特殊的性质，使它们具有量子点发射率，并且安全且易于根据不同的应用进行修改。在这个项目中创建的新的QD试剂平台将为生物和医学成像提供优越的荧光团。

DESCRIPTION (provided by applicant): Quantum dots are recognized as the core materials of a new generation luminescent agents for biolabelling applications. This project will establish proof-of-concept for a new class of non-toxic, metal free quantum dot-like materials. We will synthesize these new materials, derivatize them for water solubility, and characterize their compositions and their emission properties. These materials have particular properties which give them quantum-dot emissivity, and are safe and readily modifiable for different applications. The platform for new QD agents created in this project will offer superior fluorophores for biological and medial imaging.