Baylor-Cayetano Heredia Training Program in Global Infe*

全球 Infe* 贝勒-卡耶塔诺埃雷迪亚培训计划

• 批准号: 7037645
• 负责人: Arthur Clinton White
• 金额: $ 8.35万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-01 至 2006-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7037645
• 关键词: Peru; clinical research; diarrhea; epidemiology; health care personnel education; helminthiasis; human subject; immunology; international cooperation; parasitic gastrointestinal disorder; physicians; postgraduate education; protozoal infection; training; tropical medicine

DESCRIPTION (provided by applicant): This is a new training grant submitted for the Global Infectious Disease Research Training Program. This program will take advantage of the rich investigative environment at Baylor College of Medicine (BCM) to train outstanding physicians from the Institute of Tropical Medicine (IMT), Universidad Peruana Cayetano Heredia. Training will focus on diseases targeted by IMT, taking advantage of ongoing research opportunities in clinical and laboratory investigation at BCM in diarrheal diseases and immunoparasitology. One trainee will be selected to enter the proposed training program per year by a committee headed by IMT faculty based on the candidate's outstanding academic potential and commitment to return to Peru to work at IMT in global infectious diseases. Each trainee will undergo 2 years of rigorous scientific training at BCM. Trainees will enroll in courses from BCM's graduate school and BCM's NIH K30-supported clinician scientist training program, providing them a strong knowledge base in immunology or epidemiology, principals of conducting clinical research, and ethical conduct of research. Trainees will be comprehensively mentored in hypothesis-driven research, preparation of manuscripts for publication, presentations at national meetings, preparation of grant proposals, and academic career development. Trainees in immunoparasitology will work in the BCM Biology of Inflammation Center, which includes 20,000 sq ft of contiguous, newly renovated laboratory space and houses a highly interactive critical mass of investigators and trainees, focused on the immune response. Mentors, selected from NIH-funded principal investigators in the center, will provide training in the human mucosal immune response, cellular immunology and cytokine/chemokine interactions related to intestinal protozoan and helminth infections. Training in diarrheal disease will be based at the Center for Infectious Diseases, at the University of Texas School of Public Health. Trainees will work in collaboration with ongoing international investigations of diarrheal diseases in travelers and endemic populations or with the NIH-sponsored enteric challenge core of the BCM vaccine treatment evaluation unit. All trainees and their BCM mentors will be required to submit grant applications during the second year of training. During a third year, trainees will receive salary support during their initial 6 months on the IMT faculty, allowing them protected time to establish independent research agendas and time to establish collaborations. The goals of this training program are to develop and mentor physician-scientists committed to global infectious diseases, to provide them with the tools needed to obtain independent funding, and mentor them as international leaders in global Infectious Diseases.

描述（由申请人提供）：这是为全球传染病研究培训计划提交的新培训补助金。该项目将利用贝勒医学院（BCM）丰富的研究环境，培养秘鲁卡耶塔诺埃雷迪亚大学热带医学研究所（IMT）的优秀医师。培训将重点关注 IMT 所针对的疾病，利用 BCM 在腹泻疾病和免疫寄生虫学方面正在进行的临床和实验室研究的研究机会。由 IMT 教员领导的委员会每年将根据候选人的杰出学术潜力和返回秘鲁在 IMT 全球传染病领域工作的承诺，选出一名学员参加拟议的培训计划。每位学员都将在BCM接受2年严格的科学培训。学员将参加 BCM 研究生院和 BCM NIH K30 支持的临床科学家培训计划的课程，为他们提供免疫学或流行病学、临床研究原则和研究道德行为方面的强大知识基础。学员将在假设驱动的研究、出版手稿的准备、在全国会议上的演讲、拨款提案的准备和学术职业发展方面接受全面指导。免疫寄生虫学的学员将在 BCM 炎症生物学中心工作，该中心包括 20,000 平方英尺的新装修的连续实验室空间，并容纳了高度互动的关键数量的研究人员和学员，重点关注免疫反应。从该中心由 NIH 资助的主要研究人员中选出的导师将提供人类粘膜免疫反应、细胞免疫学以及与肠道原生动物和蠕虫感染相关的细胞因子/趋化因子相互作用方面的培训。腹泻病培训将在德克萨斯大学公共卫生学院传染病中心进行。学员将与正在进行的旅行者和地方性人群腹泻疾病的国际调查合作，或与 NIH 资助的 BCM 疫苗治疗评估部门的肠道挑战核心合作。所有学员及其 BCM 导师都需要在培训的第二年提交资助申请。在第三年，学员将在 IMT 教员的最初 6 个月内获得工资支持，使他们有受保护的时间来建立独立的研究议程和建立合作。该培训计划的目标是培养和指导致力于全球传染病研究的医师科学家，为他们提供获得独立资金所需的工具，并指导他们成为全球传染病领域的国际领导者。