STRUCTURE-FUNCTION OF TRANSCOBALAMIN II AND ITS RECEPTOR
STRUCTURE-FUNCTION OF TRANSCOBALAMIN II AND ITS RECEPTOR
批准号:
6717706
负责人:
Bellur Seetharam
金额:
$20.18万
依托单位国家:
美国
项目类别:
财政年份:
1996
资助国家:
美国
项目状态:
已结题
起止时间:
1996-08-01 至 2006-01-31
关键词:
binding proteinsbiological transportcellular polaritycobalamincofactorcortisonegastrointestinal epitheliumgastrointestinal nutrient absorptionhuman tissueimmunoprecipitationlaboratory ratnorthern blottingsnutrition related tagprotein structure functionreceptor bindingsite directed mutagenesistissue /cell culturetransfectiontransport proteinsvitamin B12vitamin receptorwestern blottings
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Transcobalamin II receptor interacts with megalin in the renal apical brush border membrane.
钴胺素 II 受体与肾尖刷状缘膜中的巨蛋白相互作用。
DOI:
10.1007/s00232-002-2007-3
发表时间:
2003
期刊:
The Journal of membrane biology
影响因子:
--
作者:
[Yammani,RR, Seetharam,S, Dahms,NM, Seetharam,B]
通讯作者:
Seetharam,B
Effects of interferon beta on transcobalamin II-receptor expression and antitumor activity of nitrosylcobalamin.
干扰素β对转钴胺素II受体表达和亚硝酰钴胺素抗肿瘤活性的影响。
DOI:
10.1093/jnci/94.13.1010
发表时间:
2002
期刊:
Journal of the National Cancer Institute
影响因子:
--
作者:
[Bauer,JosephA, Morrison,BeiH, Grane,RonaldW, Jacobs,BarbaraS, Dabney,Sally, Gamero,AnaM, Carnevale,KevinA, Smith,DanielJ, Drazba,Judith, Seetharam,Bellur, Lindner,DanielJ]
通讯作者:
Lindner,DanielJ
Rat transcobalamin: cloning and regulation of mRNA expression.
大鼠转钴胺素:mRNA 表达的克隆和调节。
DOI:
10.1113/jphysiol.2003.058727
发表时间:
2004
期刊:
The Journal of physiology.
影响因子:
--
作者:
[Kalra,Seema, Seetharam,Shakuntla, Yammani,RaghunathaR, Seetharam,Bellur]
通讯作者:
Seetharam,Bellur
Brefeldin A (BFA) inhibits basolateral membrane (BLM) delivery and dimerization of transcobalamin II receptor in human intestinal epithelial Caco-2 cells. BFA effects on BLM cholesterol content.
Brefeldin A (BFA) 抑制人肠上皮 Caco-2 细胞中转钴胺素 II 受体的基底外侧膜 (BLM) 递送和二聚化。
DOI:
10.1074/jbc.273.26.16163
发表时间:
1998
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
[Bose,S, Chapin,SJ, Seetharam,S, Feix,J, Mostov,KE, Seetharam,B]
通讯作者:
Seetharam,B
A 69-base pair fragment derived from human transcobalamin II promoter is sufficient for high bidirectional activity in the absence of a TATA box and an initiator element in transfected cells. Role of an E box in transcriptional activity.
在转染细胞中缺乏 TATA 盒和起始元件的情况下,源自人转钴胺素 II 启动子的 69 碱基对片段足以实现高双向活性。
DOI:
10.1074/jbc.273.43.28170
发表时间:
1998
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
[Li,N, Seetharam,B]
通讯作者:
Seetharam,B
共 11 条
STRUCTURE-FUNCTION OF TRANSCOBALAMIN II AND ITS RECEPTOR
-
批准号:6635047
-
项目类别:
-
资助金额:$20.18万
-
财政年份:1996
-
负责人:Bellur Seetharam
-
依托单位:
RECEPTOR MEDIATED ENDOCYTOSIS OF COBALAMIN (VITAMIN B12)
-
批准号:2749553
-
项目类别:
-
资助金额:$14.37万
-
财政年份:1996
-
负责人:Bellur Seetharam
-
依托单位:
STRUCTURE-FUNCTION OF TRANSCOBALAMIN II AND ITS RECEPTOR
-
批准号:6381002
-
项目类别:
-
资助金额:$20.18万
-
财政年份:1996
-
负责人:Bellur Seetharam
-
依托单位:
RECEPTOR MEDIATED ENDOCYTOSIS OF COBALAMIN (VITAMIN B12)
-
批准号:2458891
-
项目类别:
-
资助金额:$13.82万
-
财政年份:1996
-
负责人:Bellur Seetharam
-
依托单位:
RECEPTOR MEDIATED ENDOCYTOSIS OF COBALAMIN (VITAMIN B12)
-
批准号:2151039
-
项目类别:
-
资助金额:$13.29万
-
财政年份:1996
-
负责人:Bellur Seetharam
-
依托单位:
STRUCTURE-FUNCTION OF TRANSCOBALAMIN II AND ITS RECEPTOR
-
批准号:6517362
-
项目类别:
-
资助金额:$20.18万
-
财政年份:1996
-
负责人:Bellur Seetharam
-
依托单位:
STRUCTURE-FUNCTION OF TRANSCOBALAMIN II AND ITS RECEPTOR
-
批准号:6094181
-
项目类别:
-
资助金额:$20.18万
-
财政年份:1996
-
负责人:Bellur Seetharam
-
依托单位:
STUDIES ON INTESTINAL BRUSH BORDER MEMBRANES
-
批准号:3227976
-
项目类别:
-
资助金额:$8.27万
-
财政年份:1988
-
负责人:Bellur Seetharam
-
依托单位:
STUDIES ON INTESTINAL BRUSH BORDER MEMBRANES
-
批准号:3227971
-
项目类别:
-
资助金额:$10.35万
-
财政年份:1979
-
负责人:Bellur Seetharam
-
依托单位:
STUDIES ON INTESTINAL BRUSH BORDER MEMBRANES
-
批准号:3227972
-
项目类别:
-
资助金额:$14.18万
-
财政年份:1979
-
负责人:Bellur Seetharam
-
依托单位:
STUDIES ON INTESTINAL BRUSH BORDER MEMBRANES
-
批准号:3227968
-
项目类别:
-
资助金额:$6.35万
-
财政年份:1979
-
负责人:Bellur Seetharam
-
依托单位:
INTESTINAL BRUSH BORDER MEMBRANES
-
批准号:2137891
-
项目类别:
-
资助金额:$17.27万
-
财政年份:1979
-
负责人:Bellur Seetharam
-
依托单位:
INTESTINAL BRUSH BORDER MEMBRANES
-
批准号:2439689
-
项目类别:
-
资助金额:$10.87万
-
财政年份:1979
-
负责人:Bellur Seetharam
-
依托单位:
STUDIES ON INTESTINAL BRUSH BORDER MEMBRANES
-
批准号:3227970
-
项目类别:
-
资助金额:$9.83万
-
财政年份:1979
-
负责人:Bellur Seetharam
-
依托单位:
INTESTINAL BRUSH BORDER MEMBRANES
-
批准号:2137892
-
项目类别:
-
资助金额:$17.94万
-
财政年份:1979
-
负责人:Bellur Seetharam
-
依托单位:
STUDIES ON INTESTINAL BRUSH BORDER MEMBRANES
-
批准号:3227974
-
项目类别:
-
资助金额:$15.5万
-
财政年份:1979
-
负责人:Bellur Seetharam
-
依托单位:
STUDIES ON INTESTINAL BRUSH BORDER MEMBRANES
-
批准号:3151652
-
项目类别:
-
资助金额:$9.24万
-
财政年份:1979
-
负责人:Bellur Seetharam
-
依托单位:
INTESTINAL BRUSH BORDER MEMBRANES
-
批准号:3227969
-
项目类别:
-
资助金额:$17.04万
-
财政年份:1979
-
负责人:Bellur Seetharam
-
依托单位:
INTESTINAL BRUSH BORDER MEMBRANES
-
批准号:3227975
-
项目类别:
-
资助金额:$16.23万
-
财政年份:1979
-
负责人:Bellur Seetharam
-
依托单位:
STUDIES ON INTESTINAL BRUSH BORDER MEMBRANES
-
批准号:3227973
-
项目类别:
-
资助金额:$14.52万
-
财政年份:1979
-
负责人:Bellur Seetharam
-
依托单位:
海外基金