EXTRAMURAL RESEARCH FACILITIES IMPROVEMENT

描述(由申请人提供)： 在过去的五年里，新泽西医学院成功地遵循了其积极扩大研究项目的战略计划。自1998年以来，NIH的资金几乎增加了两倍。该学院目前的计划是发展一个癌症中心，该中心将容纳基础和临床研究以及门诊治疗项目。该大学和医学院已承诺提供资金，用于建造一座新的18.5万平方英尺的建筑，并招聘更多从事基础和翻译研究的教职员工。大楼目前正在施工，预计于2005年12月完工。 这项建议的长远目标是： *发展研究动物设施，以充分支持我们所有资助的研究计划 *创造一种环境，使一批受资助的研究人员能够开发针对癌症的跨学科计划；包括癌症分子生物学、基因表达和细胞生长控制的分子机制、体内实验以及将其转化为临床治疗方案的平台研究 *提供足够的空间和资源，培训博士和医学博士/博士研究生、博士后研究员和住院医师参加培训计划 作为一所拥有西班牙裔卓越中心的医学院，我们正在申请400万美元的配套资金，用于在UMDNJ-新泽西医学院癌症中心(癌症中心)建设一个19545平方英尺的老鼠屏障设施。这些资金将专门用于建造(在无人居住的空壳空间，目前正在建设中)老鼠屏障研究设施，供实验室设在癌症中心的研究人员使用。不为基础科学研究实验室或癌症中心的任何临床领域寻求资金。

DESCRIPTION (provided by applicant): Over the past five years, the New Jersey Medical School has successfully followed its strategic plan to aggressively expand its research programs. NIH funding has close to tripled since 1998. The School's current initiative is to develop a Cancer Center that will house basic and clinical research as well as outpatient treatment programs. The University and the Medical School have committed funds for construction of a new 185,000 sq ft building and the recruitment of additional faculty who will pursue basic and translational research. Construction of the building is now under way with an anticipated completion date in December 2005. The long-term objectives of this proposal are to: *Develop research animal facilities to adequately support all of our funded research programs *Create an environment that will enable a cadre of funded researchers to develop interdisciplinary programs that target cancer; encompassing bench research in the molecular biology of cancer, molecular mechanisms of gene expression and cell growth control, in vivo experimentation, and its translation into clinical treatment regimens *Provide adequate space and resources to train PhD and MD/PhD graduate students, postdoctoral fellows and residents pursuing training programs As a medical school with an Hispanic Center of Excellence, we are requesting $4 million in matching funds toward the construction of a 19,545 gross square foot Mouse Barrier Facility in the UMDNJ - New Jersey Medical School Cancer Center (Cancer Center). These funds will be used exclusively for the purpose of constructing (in uninhabited shell space, currently under construction) a Mouse Barrier Research Facility for use by investigators whose laboratories are housed in the Cancer Center. No funds are sought for basic science research laboratories or any clinical areas in the Cancer Center.