Are genetic risk scores useful in developing precise public health guidelines that aim to reduce the risks of Vitamin B12 deficiency among vegan pregn

遗传风险评分对于制定旨在降低纯素孕妇维生素 B12 缺乏风险的精确公共卫生指南是否有用

• 批准号: 2601526
• 金额: --
• 依托单位: University of Surrey
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2021
• 资助国家: 英国
• 起止时间: 2021 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2601526
• 关键词: genetic; risk; scores; useful; developing

Rapid advances in technology now enable us to leverage genomic data, based on polygenic risk scores (PRS), alongside traditional risk indices, to develop more 'precise' approaches to addressing malnutrition across life-course. It is expected that such 'precision public health' (PPH) initiatives will radically transform current population-based nutritional approaches, by moving towards a more "individualised" diagnosis and treatment. It is believed that PPH approaches will lead to major cuts in healthcare costs as "people" can and will make preventive lifestyle changes (PMID: 31362796).

技术的快速进步现在使我们能够利用基于多基因风险评分（PRS）的基因组数据，以及传统的风险指数，开发更“精确”的方法来解决整个生命过程中的营养不良问题。预计这种“精准公共卫生”（PPH）举措将通过转向更加“个性化”的诊断和治疗，从根本上改变目前以人口为基础的营养方法。据信，PPH方法将导致医疗保健成本的大幅削减，因为“人们”可以并将做出预防性的生活方式改变（PMID：31362796）。