Facilitating the increase in pulmonary blood flow at birth

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Pulmonary hypertension in newborn infants is a significant problem that is very difficult to treat because we do not understand how blood flow through the lungs increases at birth. We have recently shown that currently believed mechanisms controlling blood flow at birth are incorrect and additional factors exist. Our experiments will determine factors that affect blood flow through the lungs at birth. This information will be used to improve the care of newborns with pulmonary hypertension.