Penn State: ABSL-3 Facility Construction

描述（由申请人提供）：宾夕法尼亚州立大学拟新建一座1，858平方米（20，000 GSF）的动物生物安全三级（ABSL-3）建筑。这一设施是迫切需要支持扩大研究计划，在新兴的病原体，人畜共患病，病媒传播的疾病，宿主病原体界面，和疫苗的发展。由于目前校园内没有ABSL-3空间，这座建筑将满足对空间的重大需求，以安全地研究高传染性病原体。该建筑将包括微生物学和病毒学实验室，细胞分选能力，动物生物遏制套房和昆虫。19名教师研究人员计划利用这一新设施。此外，宾州州立大学正在积极招募6-12名传染病和病原体进化领域的新教员。这座大楼将加强我们的招聘工作，并使我们能够扩大我们在传染病方面的研究工作。宾夕法尼亚州立大学早就认识到需要一个ABSL-3设施。2007年制定了初步计划，但该项目没有启动（因为项目估计数几乎是现有预算的三倍）。宾州州立大学承诺拨款800万美元，并要求1500万美元完成估计2300万美元的项目。我们已经组建了一个具有相当丰富的ABSL-3经验的项目团队，将在预算内按时完成我们的绿色和可持续建筑，在此过程中创造了320多个美国就业机会。除了上述新的教职员工外，宾夕法尼亚州立大学还致力于聘请ABSL-3设施经理和其他工作人员，并为设施的维护和运营提供持续的预算支持。

DESCRIPTION (provided by applicant): Penn State proposes to build a new 1,858 m2 (20,000 GSF) animal biosafety level three (ABSL-3) building. This facility is critically needed to support expanding research programs in emerging pathogens, zoonoses, vector borne diseases, the host pathogen interface, and vaccine development. As there is currently no ABSL-3 space on campus, this building will fulfill a significant need for space to safely study highly infectious agents. The building will include microbiology and virology laboratories, cell sorting capabilities, animal biocontainment suites, and an insectary. Nineteen faculty researchers have plans to utilize this new facility. In addition, Penn State is actively recruiting 6-12 new faculty members in the area of infectious disease and pathogen evolution. This building will enhance our recruiting efforts, and allow us to broaden our research efforts in infectious disease. Penn State has long recognized the need for an ABSL-3 facility. Initial plans were developed in 2007, but the project was not initiated (as project estimates were nearly triple the available budget). Penn State is committed to allocating $8 million, and requests $15 million to complete the estimated $23 million project. We have assembled a project team with considerable ABSL-3 experience that will complete our green and sustainable building within budget and on time, creating over 320 American jobs in the process. In addition to the new faculty members above, Penn State is committed to hiring an ABSL-3 facility manager and other staff, as well as providing ongoing budgetary support for the maintenance and operation of the facility.