Extramural Research Facilities Construction

描述(由申请人提供)： 内布拉斯加州病毒学中心(NCV)是NCRR生物医学研究卓越中心的设施，是内布拉斯加州大学林肯分校(UNL)最优先建设的设施。NCV的科学家对人类、动物和植物病毒进行基础研究，包括艾滋病毒、疱疹病毒、人类乳头瘤病毒、PRRSV和人畜共患病，最终目标是开发治疗和预防疾病的新策略。 NCV研究为UNL的五年PHS资金增加了336%做出了巨大贡献，这一成功导致了生物医学研究空间的严重短缺。NCV的科学家分散在两个校区，阻碍了NCV项目的研究和扩展。这种空间的缺乏导致两名资深科学家的损失，并阻碍了计划中的招聘。 对研究空间的迫切需求迫使联合国后勤基地开始建造一个60,000平方英尺的设施外壳。这项提议的目标是完善这一外壳，完成一个设施，容纳NCV的科学家、学生和工作人员，将所有UNL传染病研究人员安置在附近，并最大限度地利用邻近的兽医和生物医学研究设施。该建议的具体目标是： 1.提供一个集中的、可扩展的设施，容纳人类、动物和植物病毒学家，创造在模型系统上进行合作的绝佳机会，导致了解和治疗传染病的新方法； 2.增加高质量的研究空间，使NCV计划和其他高优先级生物医学研究得以扩大； 3.建立一个以传染病研究综合体为基础的设施，用于针对新出现和再次出现的传染病的基础研究。

DESCRIPTION (provided by applicant): A facility for the Nebraska Center for Virology (NCV), an NCRR Center of Biomedical Research Excellence, is the highest facility construction priority of the University of Nebraska-Lincoln (UNL). NCV scientists conduct basic research on human, animal, and plant viruses, including HIV, herpesvirus, human papillomavirus, PRRSV, and zoonotic viral diseases, with the ultimate goal of developing new strategies to treat and prevent disease. NCV research has contributed substantially to UNL's five-year, 336% increase in PHS funding, success that has led to a critical shortage in biomedical research space. NCV scientists are scattered across two campuses, impeding research and expansion of NCV programs. This lack of space has led to the loss of two senior scientists and is hindering planned recruitment. The urgent need for research space compelled UNL to initiate construction of a 60,000 square foot facility shell. The objective of this proposal is to fit-out this shell, completing a facility to house NCV scientists, students, and staff, locating all UNL infectious disease researchers in close proximity and making maximum use of adjacent veterinary and biomedical research facilities. Specific aims of the proposal are to: 1. Provide a centralized, expandable facility housing human, animal, and plant virologists, creating exceptional opportunities to collaborate on model systems, leading to new approaches to understanding and treating infectious disease; 2. Increase high quality research space to enable expansion of NCV programs and other high-priority biomedical research; 3. Develop a facility anchoring an infectious disease research complex for basic research against emerging and re-emerging infectious diseases.