2006 Lipoprotein Metabolism Gordon Conference

描述（由申请人提供）： 此申请是部分支持2006年戈登研究会议上脂蛋白代谢将在山举行。霍利奥克，学院在南哈德利，马萨诸塞州于2006年7月2日至7日。本次会议将重点关注脂质和脂蛋白代谢的重要新进展，特别是在那些影响人类代谢疾病和动脉粥样硬化血管疾病发展的领域。将介绍基本的分子和细胞生物学研究以及人体和动物模型的体内研究。主题将包括脂质在发育中的作用，载脂蛋白的结构和功能，动脉粥样硬化中的高密度脂蛋白炎症和氧化，脂蛋白代谢的人类遗传学， 高脂血症诱导的动脉粥样硬化，脂质代谢的分子生理学，通过核受体调节脂质合成和转运，ABC转运蛋白，以及脂质摄取和储存。计划举行九次会议： 1.脂质在发育中的新作用 2.载脂蛋白结构与功能 3.动脉粥样硬化中的HDL、炎症和氧化 4.脂蛋白转运的遗传决定因素 5.高血压致动脉粥样硬化的机制 6.脂质代谢分子生理学 7.核激素受体对脂蛋白代谢的调节 8. ABC转运蛋白 9.脂质摄取和储存 本次会议将是脂蛋白和脂质代谢的最新发展的介绍和整合的主要工具。重点将放在深入介绍和深入讨论新的，基本上未发表的研究。戈登脂蛋白代谢研究会议的重要目标是包括合格专业人员的多样性，并促进年轻研究人员，博士后研究员，研究生和高级研究人员之间的互动。

DESCRIPTION (provided by applicant): This application is for partial support of the 2006 Gordon Research Conference on Lipoprotein Metabolism to be held at Mt. Holyoke, College in South Hadley, MA on July 2-7, 2006. This conference will focus on important new developments in lipid and lipoprotein metabolism, particularly in those areas that impact on human metabolic disease and the development of atherosclerotic vascular disease. Basic molecular and cell biological studies and in vivo studies in humans and animal models will be presented. Topics will include the role of lipids in development, apoprotein structure and function, high density lipoprotein inflammation and oxidation in atherosclerosis, human genetics of lipoprotein metabolism, mechanism of hyperlipidemia-induced atherosclerosis, molecular physiology of lipid metabolism, regulation of lipid synthesis and transport by nuclear receptors, ABC transporters, and lipid uptake and storage. Nine sessions are planned: 1. Emerging Role of Lipids in Development 2. Apoprotein Structure and Function 3. HDL, Inflammation and Oxidation in Atherosclerosis 4. Genetic Determinants of Lipoprotein Transport 5. Mechanisms of Hyperlipidemia-induced Atherosclerosis 6. Molecular physiology of lipid metabolism 7. Regulation of Lipoprotein Metabolism by Nuclear Hormone Receptors 8. ABC Transporters 9. Lipid Uptake and Storage This conference will be a major vehicle for the presentation and integration of the latest developments in lipoprotein and lipid metabolism. Emphasis will be placed on in-depth presentations and thorough discussions of new, largely unpublished studies. Important aims of the Gordon Research Conference on Lipoprotein Metabolism are to include the diversity of qualified professionals and to foster interactions among young investigators, post-doctoral fellows, graduate students, and senior investigators.