2006 Lipoprotein Metabolism Gordon Conference

描述(由申请人提供)： 这项申请是为了部分支持2006年戈登脂蛋白代谢研究会议在Mt.霍利奥克，马萨诸塞州南哈德利学院，2006年7月2日至7日。本次会议将聚焦于脂和脂蛋白代谢方面的重要新进展，特别是那些影响人类代谢性疾病和动脉粥样硬化性血管疾病发展的领域。将介绍基础分子和细胞生物学研究以及在人类和动物模型中的活体研究。主题包括脂类在发育中的作用，载脂蛋白的结构和功能，高密度脂蛋白在动脉粥样硬化中的炎症和氧化，人类脂蛋白代谢的遗传学， 高脂血症导致的动脉粥样硬化，脂类代谢的分子生理学，核受体对脂类合成和运输的调节，ABC转运体，以及脂类的吸收和储存。计划举办九次会议： 1.脂类在发育中的新作用 2.载脂蛋白的结构和功能 3.动脉粥样硬化中的高密度脂蛋白、炎症和氧化 4.脂蛋白转运的遗传决定因素 5.高脂血症致动脉粥样硬化的机制 6.脂类代谢的分子生理学 7.核激素受体对脂蛋白代谢的调节 8.ABC运输商 9.脂肪的摄取和储存 这次会议将是介绍和整合脂蛋白和脂代谢最新发展的主要工具。重点将放在对新的、基本上未发表的研究进行深入介绍和彻底讨论上。戈登脂蛋白代谢研究会议的重要目标是包括合格专业人员的多样性，并促进年轻研究人员、博士后研究员、研究生和高级研究人员之间的互动。

DESCRIPTION (provided by applicant): This application is for partial support of the 2006 Gordon Research Conference on Lipoprotein Metabolism to be held at Mt. Holyoke, College in South Hadley, MA on July 2-7, 2006. This conference will focus on important new developments in lipid and lipoprotein metabolism, particularly in those areas that impact on human metabolic disease and the development of atherosclerotic vascular disease. Basic molecular and cell biological studies and in vivo studies in humans and animal models will be presented. Topics will include the role of lipids in development, apoprotein structure and function, high density lipoprotein inflammation and oxidation in atherosclerosis, human genetics of lipoprotein metabolism, mechanism of hyperlipidemia-induced atherosclerosis, molecular physiology of lipid metabolism, regulation of lipid synthesis and transport by nuclear receptors, ABC transporters, and lipid uptake and storage. Nine sessions are planned: 1. Emerging Role of Lipids in Development 2. Apoprotein Structure and Function 3. HDL, Inflammation and Oxidation in Atherosclerosis 4. Genetic Determinants of Lipoprotein Transport 5. Mechanisms of Hyperlipidemia-induced Atherosclerosis 6. Molecular physiology of lipid metabolism 7. Regulation of Lipoprotein Metabolism by Nuclear Hormone Receptors 8. ABC Transporters 9. Lipid Uptake and Storage This conference will be a major vehicle for the presentation and integration of the latest developments in lipoprotein and lipid metabolism. Emphasis will be placed on in-depth presentations and thorough discussions of new, largely unpublished studies. Important aims of the Gordon Research Conference on Lipoprotein Metabolism are to include the diversity of qualified professionals and to foster interactions among young investigators, post-doctoral fellows, graduate students, and senior investigators.