Frontiers in Myogenesis

描述（由申请人提供）：现申请部分资金，以支持将于2006年4月27日至5月2日在乔治亚州松山卡拉威花园举行的“肌发生前沿”国际会议。20年来，该会议每三年举行一次，最初作为基石研讨会，自2000年起独立举行。会议的重点是诱导和调节肌肉发生、神经-肌肉相互作用和人类骨骼肌疾病的分子信号和机制。这个会议通常会吸引来自世界各地的大约300名与会者。这次会议在肌肉生物学界是独一无二的，因为它的使命是汇集世界上肌肉发育和分子生物学基础科学的专家，交流他们的最新发现，并为人类肌肉疾病的诊断、预防和治疗开辟新的方向。36位受邀演讲者中的大多数已经接受了邀请，在以下9个全体会议上展示他们最激动人心的发现：胚胎中的生长发育和肌肉发生，肌纤维形成的调节，信号转导，肌肉发生的基因调节机制，肌肉的模式，肌肉干细胞和卫星细胞，肌肉疾病，神经-肌肉相互作用，肌肉质量的调节。另外36位演讲者将从提交的摘要中选择进行简短的演讲，允许包括最新的结果，并为博士后和研究生提供一个向大量听众发表演讲的机会，因为初级研究人员将优先考虑。还将举行三次晚间海报会议。今年新增了两个下午的技术研讨会，专门讨论最先进的技术，并由该领域的专家主持。我们期望，自2003年上次会议以来，基因组学、细胞和分子生物学的重大进展将使即将在格鲁吉亚举行的这次会议成为基础肌肉发育和疾病工作者相互学习的重要聚会，从而促进思想的交叉受精和进一步的进步。

DESCRIPTION (provided by applicant): Funds are requested for partial support to convene an international meeting on "Frontiers in Myogenesis" to be held April 27- May 2, 2006 at Callaway Gardens, Pine Mountain, Georgia. This meeting has been held every three years for two decades, initially as a Keystone Symposium and independently since 2000. The conference focuses on molecular signals and mechanisms that induce and regulate myogenesis, nerve-muscle interactions, and human diseases of skeletal muscle. This meeting typically attracts approximately 300 participants from all over the world. This conference is unique in the muscle biology community because of its mission to bring together the world's experts in fundamental science of muscle developmental and molecular biology to exchange their latest findings and spearhead new directions for future advances in diagnosis, prevention and therapy of muscle diseases in human. Most of the 36 invited speakers have already accepted the invitation to present their most exciting findings in the following 9 plenary sessions: Somitogenesis and myogenesis in the embryo, Regulation of myofiber formation, Signal transduction, Gene regulatory mechanisms in myogenesis, Patterning of muscle, Muscle stem cells and satellite cells, Muscle diseases, Nerve-muscle interactions, and Regulation of muscle mass. An additional 36 speakers will be chosen from submitted abstracts for short talks, allowing the inclusion of the latest results and providing an opportunity for postdoctoral fellows and graduate students to address a large audience, as priority will be given to junior investigators. Three evening poster sessions will also take place. New this year are two afternoon technology workshops devoted to state-of-the-art technologies and moderated by experts in the field. We expect the major advances in genomics, cellular and molecular biology that took place since the last conference in 2003 will make this upcoming meeting in Georgia an essential gathering for workers in both basic muscle development and disease to learn from each other and therefore, stimulate a cross fertilization of ideas and further advances.