Obstacles to Translating Basic Knowledge of Genetic Skin Disease into Therapies

将遗传性皮肤病的基本知识转化为治疗方法的障碍

• 批准号: 7294523
• 负责人: Ervin HAROLD Epstein
• 金额: $ 2.5万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-30 至 2006-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7294523
• 关键词: genetic disorder; meeting /conference /symposium; skin disorder; skin disorder chemotherapy; travel

DESCRIPTION (provided by applicant): This application requests support for a Conference addressing the Obstacles impeding translation of fundamental knowledge of gene defects in heritable skin disorders into practical, molecularly-targeted therapies for these diseases. The Obstacles to be addressed will include Obstacles to Identification and Production of Useful Molecules, Obstacles to the Delivery of Molecules into the Living Skin and immunologic Obstacles to their Use; Regulatory Obstacles; and Financial Obstacles to Drug Discovery and Development. The Conference first will delineate these obstacles and second will focus on strategies for overcoming the challenges they present. The long-term goal is to stimulate translational research for those skin diseases in which the fundamental cause now is known, and it is expected that the lessons of that research also eventually will be applicable not only to the broader range of skin diseases for which the fundamental defect now is not known but also more generally to the development of molecularly-targeted therapies.

描述（由申请人提供）：