Hereditary Multiple Exostoses: Insights Into Pathogenesis

遗传性多发性外生骨疣：发病机制的见解

• 批准号: 7144464
• 负责人: DAN E WELLS
• 金额: $ 2万
• 依托单位: UNIVERSITY OF HOUSTON
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-30 至 2006-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7144464
• 关键词: Hereditary; Multiple; Exostoses; Insights; Into

DESCRIPTION (provided by applicant): The primary objective of the conference is to establish a clinical and research community devoted to understanding and treating Hereditary Multiple Exostosis (HME). This will be accomplished by bringing together basic researchers and orthopedic physicians, medical geneticists, and families with HME. The meeting will facilitate discussion and collaboration both among and between all groups, accelerating the integration of current knowledge and identifying new areas with future research potential. The three day conference to be held at the Shriners Hospital for Children in Houston, TX is scheduled for November 3, 4, 5, 2005, and will bring together 40 participants. This includes 30-35 speakers and 5-10 non-speaking discussants. The non-speaking discussants are other experts in the field of HME and bone development and disease and members of the MHE Coalition, a co-sponsor of the conference. All conference participants will be involved in the entire conference and will be required to attend all sessions. The last day of the conference will include individuals and families with HME who will be invited to participate. There will be 7 scientific sessions including: Introduction/Clinical Genetics; Medical/Orthopedic considerations; EXT Function/ Biochemistry; Non-vertebrate Models; Bone Development I; Bone Development II; Exostoses/Cancer; Non-bone phenotypes/EXT-like genes; Related Bone diseases; HME Workshop. Each session will have approximately three to four invited speakers who will present 20 minute talks followed by 10 minutes of discussion. We will encourage all speakers to generalize their findings with regard to its biological context and significance so that it will be accessible to all participants. Informal discussion will also be encouraged outside of the formal sessions during meals and after the afternoon sessions. It is hoped that these discussions will promote new interactions and collaborations between participants.

描述(由申请人提供)：会议的主要目标是建立一个临床和研究社区，致力于了解和治疗遗传性多发性外生性骨瘤(HME)。这将通过将基础研究人员和整形外科医生、医学遗传学家以及HME患者家庭聚集在一起来实现。会议将促进所有群体之间的讨论和合作，加速整合现有知识，并确定具有未来研究潜力的新领域。为期三天的会议将于2005年11月3日、4日、5日在德克萨斯州休斯敦的施林内斯儿童医院举行，届时将有40名与会者参加。这包括30-35名发言者和5-10名非发言者。未发言的讨论者是HME、骨骼发育和疾病领域的其他专家以及MHE联盟的成员，MHE联盟是会议的共同赞助商之一。所有与会者都将参加整个会议，并将被要求出席所有会议。会议的最后一天将邀请患有HME的个人和家庭参加。将有7个科学会议，包括：导论/临床遗传学；医学/整形外科考虑；外部功能/生物化学；非脊椎动物模型；骨发育I；骨发育II；骨软骨病/癌症；非骨表型/外部样样基因；相关骨疾病；HME研讨会。每堂课大约有三到四位受邀的演讲者，他们将发表20分钟的演讲，然后进行10分钟的讨论。我们将鼓励所有发言者就其生物学背景和意义概括他们的调查结果，以便所有与会者都能接触到。还将鼓励在正式会议之外、用餐期间和下午会议之后进行非正式讨论。希望这些讨论将促进与会者之间新的互动和合作。