Identification and optimisation of 3' synthetic UTR sequences for use in CHO-cell biomanufacturing of therapeutic proteins
Identification and optimisation of 3' synthetic UTR sequences for use in CHO-cell biomanufacturing of therapeutic proteins
用于 CHO 细胞生物制造治疗性蛋白质的 3 合成 UTR 序列的鉴定和优化
批准号：
2620774
负责人：
金额：
$0.0万
依托单位：
依托单位国家：
英国
项目类别：
Studentship
财政年份：
2021
资助国家：
英国
项目状态：
未结题
起止时间：
2021 至 --
中文摘要
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英文摘要
The Sudbery lab is primarily interested in how UTR sequences determine transcript fate, and we have developed a machine-learning-enhanced approach to screen the function of hundreds of thousands of synthetic UTR sequences in parallel to identify sequences with desired properties. The successful candidate will apply these approaches to identify and optimise 3' synthetic UTR sequences for use in the CHO-cell biomanufacturing.
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