Eighth & Ninth International Symposia on Neurobiology & Neuroendocrinology Aging

描述(申请人提供)：第八届和第九届神经生物学和神经内分泌衰老国际研讨会将于2006年7月23-28日和2008年7月在奥地利布雷根茨举行。这些会议的目的是让一群在衰老机制研究方面取得重大进展的研究人员聚集在一起，特别是在中枢神经系统衰老、神经保护、神经退行性疾病的检测和治疗方面。2006年的专题将包括线粒体和染色体dna损伤的作用、自噬、胰岛素抵抗、高级糖基化产物、应激抵抗、瘦素、伴侣和蛋白、转化生长因子β、胰岛素样生长因子-1亚型和雌激素的神经发生和神经保护作用，以及 阿尔茨海默病早期发现和治疗的新方法。此外，还将介绍有关线虫衰老的遗传学和寿命极短的脊椎动物物种的衰老的新数据。我们特意包括了广泛的主题，并召集了一群通常不会参加同一会议的科学家。会议的形式仿照戈登研究会议，鼓励对提交的材料进行正式和非正式的讨论。会议记录将在研讨会后大约6个月内作为实验老年学的特刊发表。强烈鼓励包括研究生和博士后研究员在内的初级调查人员参与，这项提案寻求为那些正在接受培训或担任初级教师职位并计划在海报会议上展示他们的发现的美国参与者提供补贴。我们还在寻求为美国特邀发言者的费用提供部分支持。

DESCRIPTION (provided by applicant): The Eighth and Ninth International Symposia on Neurobiology & Neuroendocrinology Aging will be held in Bregenz, Austria July 23-28, 2006 and in July 2008. The purpose of these meetings is to bring together a group of investigators who made recent significant advances in the study of mechanisms of aging, with particular emphasis on CNS aging, neuroprotection, detection and treatment of neurodegenerative disease. Specific topics to be covered in 2006 will include the role of damage of mitochondrial and chromosomal DNA, autophagy, insulin resistance, advanced glycation products, stress resistance, leptin, chaperones, and prions, neurogenesis and neuroprotective effects of TGF beta, IGF-1 isoforms, and estrogens, as well as novel approaches to early detection and treatment of Alzheimer's disease. In addition, new data on genetics of aging in C. elegans and on aging in an exceptionally short-lived vertebrate species will be presented. We purposely include a wide range of topics and assemble a group of scientists that may not normally attend the same meeting. The format of the meeting is modeled after Gordon Research Conferences and encourages formal and informal discussions of the material presented. Proceedings will be published as a special issue of Experimental Gerontology within approximately 6 months after the Symposium. Participation of junior investigators, including graduate students and post-doctoral fellows is strongly encouraged and this proposal seeks funds for providing stipends to those US participants who are in training or are in junior faculty positions and who are planning to present their findings in the poster session. We are also seeking partial support for the expenses of invited speakers from the United States.