ANXIETY, DEPRESSION AND ASTHMA IN PUERTO RICAN YOUTH

波多黎各青年的焦虑、抑郁和哮喘

• 批准号: 7110326
• 负责人: Alexander N Ortega
• 金额: $ 40.9万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-08-15 至 2008-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7110326
• 关键词: Puerto Rican; adolescence (12-20); anxiety disorders; asthma; caregivers; clinical depression; clinical research; comorbidity; human subject; mental health epidemiology; middle childhood (6-11); parent offspring interaction; psychological stressor; respiratory disorder epidemiology; self concept

DESCRIPTION (provided by applicant): This application responds to NIMH Program Announcement (PA) 02-047, Research on Co-Morbid Mental and Other Physical Disorders. Associations between child and adolescent psychiatric and psychological problems and parent reports of asthma have been described in the literature, and there is some evidence that the prevalence of asthma and its association with mental disorders is particularly striking in Puerto Rican youth. However, the methodological designs of previous studies have been largely limited to the use of clinical samples, cross-sectional studies, and the use of non-standardized or otherwise compromised measures of psychiatric disorders or asthma in youth. These limitations prevent interpretation of the associations in the community. The proposed study overcomes many of these limitations and would establish the magnitude of associations between anxiety and depressive disorders and asthma in Puerto Rican youth, and it would also determine the associations between caregivers' mental disorders and risk for asthma in the sample of children and adolescents. Further, it would determine the prospective relations between caregiver psychopathology, stressors, functioning and the management of childhood asthma. The study builds on two previously collected waves of data of Puerto Rican youth (R01-MH054827; Dr. Glorisa Canino), from 1999-2001. It would collect a new, third wave of data on child/adolescent and caregiver psychiatric disorders, asthma prevalence and severity, and psychosocial problems in a stratified sample of 700 youth from the original cohort. We will also take a stratified sample of 200 of the 700 subjects for spirometry testing and medical chart review. The proposed study will allow us to begin to investigate the mechanisms and clinical management consequences of co-morbid asthma and mental disorders. Overall, this study will provide useful information on two major public health problems for Hispanic youth, mental health and asthma, and begin to investigate the links between theses two critical public health issues.

描述（由申请人提供）：本申请响应NIMH计划公告（PA）02-047，共病精神和其他身体疾病的研究。儿童和青少年精神和心理问题与父母报告的哮喘之间的关联已在文献中有所描述，有一些证据表明，在波多黎各青年中，哮喘的流行及其与精神障碍的关联尤其引人注目。然而，以往研究的方法学设计在很大程度上局限于使用临床样本，横断面研究，以及使用非标准化或以其他方式损害青年精神疾病或哮喘的措施。这些限制妨碍了对社区中的社团进行解释。拟议的研究克服了许多这些局限性，并将建立焦虑和抑郁症与波多黎各青年哮喘之间的关联程度，它还将确定儿童和青少年样本中照顾者的精神障碍与哮喘风险之间的关联。此外，它将确定照顾者的精神病理学，应激源，功能和儿童哮喘的管理之间的前瞻性关系。这项研究建立在1999-2001年以前收集的两波波多黎各青年数据（R 01-MH 054827; Glorisa Canino博士）的基础上。它将收集一个新的，第三波数据的儿童/青少年和照顾者精神疾病，哮喘患病率和严重程度，以及心理社会问题的分层样本的700名青年从原来的队列。我们还将从700名受试者中抽取200名分层样本进行肺量测定和病历审查。这项研究将使我们开始研究哮喘和精神障碍共病的机制和临床管理结果。总体而言，这项研究将提供有用的信息，两个主要的公共卫生问题，西班牙裔青年，心理健康和哮喘，并开始调查这两个关键的公共卫生问题之间的联系。