Thiol-Ene Polymers as Dental Restorative Materials

描述(申请人提供)：建议的研究是开发应用于牙科修复材料的硫醇-烯聚合物。这项研究的目标是开发与目前用于牙科修复材料的聚合物相比具有更好性能的硫醇-烯材料。这项研究将包括研究化学结构、聚合动力学和材料性能之间的关系，这些研究将与 商业上可用的单体，以及Bowman和Stansbury研究小组合成的新型硫醇和烯单体。还将研究含填充颗粒的硫醇-烯基牙科复合体系。将解决的关键领域是体积收缩和收缩应力以及单体配方的稳定性。将评估单体配方与填料颗粒的相容性以及填充体系的性能。此外，还将评估新型牙科修复材料的生物相容性。

DESCRIPTION (provided by applicant): The proposed research is to develop thiol-ene polymers for application as dental restorative materials. The goals of this research are to develop thiol-ene materials that will have superior properties relative to current polymers utilized for dental restorative materials. The research will involve studying the relationship between chemical structure, polymerization kinetics, and material properties, these studies will be conducted with commercially available monomers and also novel thiol and ene monomers synthesized in the Bowman and Stansbury research groups. Thiol-ene based dental composite systems with filler particles will also be studied. Critical areas that will be addressed are volume shrinkage and shrinkage stress as well as the stability of the monomer formulations. The compatibility of monomer formulations with filler particles and the properties of filled systems will be evaluated. Biocompatibility of the new dental restorative materials will also be assessed.