Eye and head contributions to gaze stability

眼睛和头部对注视稳定性的贡献

• 批准号: 6998900
• 负责人: ASIM HAQUE
• 金额: $ 3.4万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-01-01 至 2006-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6998900
• 关键词: behavior test; behavioral /social science research tag; body movement; electrodes; eye movements; head movements; neural information processing; neurophysiology; pigeons; predoctoral investigator; space perception; vestibular pathway; vestibuloocular reflex; visual fixation

DESCRIPTION (provided by applicant): Eye and head reflexes are essential in maintaining the orientation of gaze in space at all times such that retinal images are stabilized. Although the VOR in pigeons (like all lateral-eyed animals) has been reported as undercompensatory, during natural behaviors such as flight, birds must be able to maintain gaze stability, perhaps using concerted head movement involving the VCR, CCR and inertia (head responses) to maintain steady gaze. In addition, different functional roles for vestibular afferents based on discharge dynamics have been previously proposed. Irregularly firing afferents are known to be sensitive to anodal galvanic currents which seem to have little effect upon the angular VOR. It is postulated that the irregular afferents may play a more significant role in the functional pathways of head and neck responses to motion. In the present proposed series of experiments, three-dimensional gaze stability will first be determined in pigeons during rotational and linear motion, examining the relative contributions of the eye and head. Second, the effects of altering the input from irregularly firing afferents upon gaze stability will be determined. For both objectives, quantitative measures of interest will include eye-in-space, head-in-space, and eye-in-head.

描述（由申请人提供）：眼睛和头部的反射对于始终保持凝视的空间方向至关重要，从而使视网膜图像稳定。尽管鸽子（像所有侧眼动物一样）的VOR被报道为补偿不足，但在飞行等自然行为中，鸟类必须能够保持凝视的稳定性，可能使用包括VCR， CCR和惯性（头部反应）在内的协调头部运动来保持稳定的凝视。此外，前庭传入神经在放电动力学上的不同功能作用也已被提出。不规则的放电事件被认为是敏感的阳极电流似乎对角VOR影响不大。我们推测，不规则传入可能在头颈部运动反应的功能通路中起着更重要的作用。在目前提出的一系列实验中，将首先确定鸽子在旋转和直线运动中的三维凝视稳定性，检查眼睛和头部的相对贡献。其次，将确定改变来自不规则发射传入的输入对凝视稳定性的影响。对于这两个目标，感兴趣的定量测量将包括眼对空、头对空和眼对空。