Shellfish Kinetics

描述（由申请人提供）：本中心提案的贝类动力学研究项目组成部分的作用是：对调节底栖双壳类动物积累和结合软骨藻酸的机会的物理、生态和有机过程进行预测性理解，这是滤食性伪尼齐亚和其他携带海洋毒素的微观藻类的结果。总体目标是将太平洋沿岸的海洋学和软骨藻酸以及普吉特海湾的海洋学和软骨藻酸调查与中心的人类健康和风险评估组成部分结合起来（见人类接触研究项目和信息学设施核心）。研究人员将通过比较沿海岸（软骨藻酸是一个急性问题）和普吉特海湾（只有慢性低水平暴露）的急性软骨藻酸毒性，直接与海洋学和普吉特海湾的软骨藻酸成分相结合

Description (provided by applicant): The role of the Shellfish Kinetics Research Project component of this Center proposal is to: develop a predictive understanding of the physical, ecological and organismal processes that regulate the opportunity for benthic bivalves to accumulate and bind domoic acid as a result of filter feeding Pseudo-nitzschia spp. and other microscopic algae bearing marine toxins. The overall objective is to integrate the oceanography and domoic acid on the Pacific Coast and oceanography and domoic acid in Puget Sound investigations with the human health and risk assessment components of the Center (see Human Exposure Research Project and the Informatics Facility Core). The investigators will directly interface with the oceanography and domoic acid in Puget Sound component through the comparison of acute domoic acid toxicity along the coast (where domoic acid is an acute problem) to the Puget Sound (where there are only chronic low-level exposures, with essentially no acute domoic acid toxicity). To achieve these goals the investigators have separated the Shellfish Kinetics Research Project into two projects. Project 1 will focus on comparisons between offshore/neritic and nearshore regions, with the specific goal of understanding the mechanisms underlying the flux of toxic algae from the water column into near shore benthic bivalves. The second project seeks to follow the consequence of bivalve assimilation of domoic acid.