Core--Natural products

核心--天然产物

• 批准号: 7120463
• 负责人: VESNA Ana ETEROVIC
• 金额: $ 7.93万
• 依托单位: UNIVERSIDAD CENTRAL DEL CARIBE
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-07 至 2006-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7120463
• 关键词: biological products; biomedical facility; coral; diterpenes; drug discovery /isolation; tobacco

Since cembranoids are not commercially available, it is necessary to obtain them from their natural sources: soft corals found in the tropical seas around Puerto Rico, or from tobacco leaves grown on the island. The Natural Products Core will provide the cembranoids needed in the Project 1 and Project 2 from SNRP-1, which will continue to be a part of this program for one year in order to obtain additional results needed for their RO1 grant proposals. This core will organize diving expeditions for collection of specimens, will isolate the compounds to high purity and determine their molecular structures.

由于西松烷类化合物无法在市场上买到，因此有必要从天然来源获得：波多黎各周围热带海域发现的软珊瑚，或从岛上生长的烟叶中获得。天然产品核心将提供SNRP-1项目1和项目2所需的西松烷类化合物，该项目将继续作为该计划的一部分，为期一年，以获得其RO 1赠款提案所需的额外结果。这个核心将组织潜水探险以收集标本，将化合物分离到高纯度并确定其分子结构。