Minority-Based Community Clinical Oncology Program

基于少数民族的社区临床肿瘤学计划

• 批准号: 7079442
• 负责人: Steven N. Wolff
• 金额: $ 37万
• 依托单位: MEHARRY MEDICAL COLLEGE
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-08-27 至 2007-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7079442
• 关键词: African American; cancer prevention; clinical research; clinical trials; community health services; cooperative study; health care personnel; health care service availability; human subject; human therapy evaluation; medical outreach /case finding; medically underserved population; neoplasm /cancer; neoplasm /cancer education; neoplasm /cancer therapy; patient oriented research; primary care physician; rural area; urban area

DESCRIPTION (provided by applicant): Minority populations have multiple impediments to proper health care and this disparity is nowhere more meaningful than in cancer prevention and treatment. The overall cancer death rate for African-Americans is greater than for all other ethnic groups and the disparity, measured as the ratio of black:white cancer related mortality, has even worsened from 1979 to 1998 for both males and females. Considering these facts, it is clear that greater efforts are required for minority populations. This effort must include accrual to cancer therapy (CT) and cancer prevention and control (CPC) trials where minority populations are substantially underrepresented, even correcting for relative frequency to Caucasian populations. This proposal aims to establish a mechanism to accrue greater numbers of minority patients onto CT and CPC trials, to involve primary care health care centers in the minority community and to evaluate impediments for the overall process. The specific goals of this proposal are to broaden access to cancer treatment studies for minority populations by entering substantial numbers of minority patients onto NCI approved CT and CPC studies; to increase community practicing physician participation on NCI approved studies; and to transfer new technology to health care providers caring for minority and underserved populations. Additionally, the proposal will study barriers to CPC in minority populations and examine issues in MBCCOP performance for trials including recruitment, accrual and protocol performance. The Meharry Medical College (MMC) Minority-Based Community Clinical Oncology Program (MBCCOP) is based on the dual mission of MMC to 1) educate minority physicians and 2) to treat minority and the underserved populations. MMC will serve as the centerpiece of the MBCCOP based on its active and increasing cancer treatment trials program in the catchment region of Metropolitan Davidson County (MDC) where minority populations make up approximately 33% of the entire population. The CT component of the MBCCOP will be the catchment areas largest multi-physician oncology practice (TN Oncology) already very active in clinical trials research. MBCCOP physicians will constitute 56% of all medical oncologists in the catchment area. These two groups care for large numbers of minority patients in MDC and both have a proven track record for placing patients on NCI approved protocols. MMC has a long and illustrious history in studying health care disparity and improving health care in the minority community. MMC and Vanderbilt University have extensive ongoing CT and CPC research that will serve as a foundation to expand accrual to other NCI approved trials of the research base(s). The CPC component will be an already established consortium of primary care health clinics that focus on minority and the underserved. This "Safety-Net" consortium is directed by a member of the MBCCOP and encourages research and health care delivery. This group of health care clinics, together with a novel and validated method to increase community participation in health care will be used to accrue patients onto CPC studies. The design of the MBCCOP, together with the components and established patient care methods, will allow for substantial numbers of patients to be entered onto CT and CPC studies of the NCI.

描述（由申请人提供）：少数民族人口在获得适当的医疗保健方面存在多种障碍，这种差距在癌症预防和治疗方面尤为重要。非裔美国人的总体癌症死亡率高于所有其他种族，以黑人：白人癌症相关死亡率的比例衡量，从1979年到1998年，男女之间的差距甚至更大。考虑到这些事实，显然需要为少数民族作出更大的努力。这一努力必须包括对癌症治疗（CT）和癌症预防和控制（CPC）试验的积累，在这些试验中，少数民族人群的代表性大大不足，甚至校正相对于高加索人群的频率。该提案旨在建立一种机制，使更多的少数民族患者参与CT和CPC试验，使少数民族社区的初级保健保健中心参与其中，并评估整个过程中的障碍。该提案的具体目标是通过将大量少数民族患者纳入NCI批准的CT和CPC研究，扩大少数民族人群癌症治疗研究的可及性；增加社区执业医师参与NCI批准的研究；并将新技术转让给照顾少数民族和服务不足人口的卫生保健提供者。此外，该提案将研究少数民族人口中CPC的障碍，并审查MBCCOP在试验中的绩效问题，包括招聘，应计和协议绩效。梅哈里医学院（MMC）以少数族裔为基础的社区临床肿瘤学项目（MBCCOP）基于MMC的双重使命：1)教育少数族裔医生，2)治疗少数族裔和服务不足的人群。MMC将作为MBCCOP的核心，基于其在大都会戴维森县（MDC）集水区积极和不断增加的癌症治疗试验项目，少数民族人口约占总人口的33%。MBCCOP的CT部分将是集水区最大的多医生肿瘤实践（TN oncology），已经非常活跃于临床试验研究。MBCCOP医生将占集水区所有肿瘤内科医生的56%。这两个小组在MDC照顾大量的少数民族患者，并且在将患者置于NCI批准的方案方面都有良好的记录。MMC在研究医疗保健差距和改善少数民族社区的医疗保健方面有着悠久而辉煌的历史。MMC和Vanderbilt大学正在进行广泛的CT和CPC研究，这将作为扩展到NCI批准的其他研究基地试验的基础。CPC组成部分将是一个已经成立的初级保健诊所联盟，重点是少数民族和服务不足的人。这一“安全网”联合体由妇幼保健委员会的一名成员领导，鼓励研究和提供保健服务。这组卫生保健诊所，连同一种新的和有效的方法，以增加社区参与卫生保健将被用来积累病人的CPC研究。MBCCOP的设计，连同其组成部分和已建立的患者护理方法，将允许大量患者进入NCI的CT和CPC研究。