Rules of Life - How repeatable is speciation?

物种形成涉及到基因交换障碍的建立。尽管有如此丰富的物种形成基因组案例研究，以及允许从序列变异中推断物种形成历史的方法的快速发展，但物种形成的可重复性(或特殊)程度仍不清楚，即相同的基因、基因家族和基因组区域在多大程度上参与了生殖隔离的建立。这个项目将通过对最近分化的欧洲蝴蝶物种对进行系统比较作为测试案例，来检验物种形成过程的可重复性。学生将使用一个新的统计框架来分析欧洲蝴蝶的18个姐妹对物种的种群基因组数据，该框架将序列变异模式分解为过去种群过程的基因组图(例如，基因流和背景选择)。

Speciation involves the build up of barriers to genetic exchange. Despite this wealth of speciation genomic case studies and the rapid development of methods that allow to infer speciation history from sequence variation, it remains unclear how repeatable (or idiosyncratic) speciation is, that is, to what extent the same genes, genes families and genomic regions are involved in the build up reproductive isolation. This project will examine how repeatable speciation processes are by conducting systematic comparisons between recently diverged species pairs of European butterflies as a test case. The student will analyse population genomic data 18 sister pair species of European butterfly using a novel statistical framework for decomposing patterns of sequence variation into genomic maps of past population processes (e.g. gene flow and background selection) developed in the Lohse Lab.