CORE--MORPHOLOGY FACILITY

核心——形态学设施

• 批准号: 6928204
• 负责人: BRUCE A WODA
• 金额: $ 9.14万
• 依托单位: UNIV OF MASSACHUSETTS MED SCH WORCESTER
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-04-01 至 2010-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6928204
• 关键词: biomedical facility; diabetes mellitus; histology; immunofluorescence technique; immunoperoxidase; morphology; tissue /cell preparation

A large number of diabetes-related research investigators at the University of Massachusetts Medical Center depend upon morphologic techniques to analyze their experimental models. The Morphology Core Facility satisfies the need of investigators by providing service in this area. The core provides routine histology and identification of tissue and cellular antigens utilizing immunofluorescence and immunoperoxidase techniques. The Core Director and research associate actively consult with investigators on experimental design and will train individuals in adopting these techniques in their own laboratories. The Core Director provides interpretative consultation to individual laboratories. This core enhances the productivity of Diabetes research by a) providing services not available in individual laboratories, b) allowing investigators to focus on their own projects without the need to develop their own histology and immunoperoxidase functions and 3) by encouraging interactions between investigators who share the resources of this core facility.

马萨诸塞州大学医学中心的大量糖尿病相关研究人员依赖于形态学技术来分析他们的实验模型。形态学核心设施通过提供这方面的服务来满足研究者的需要。核心提供常规组织学和组织和细胞抗原的鉴定，利用免疫荧光和免疫过氧化物酶技术。核心主任和研究助理积极与研究人员就实验设计进行磋商，并将培训个人在自己的实验室采用这些技术。核心主任向各实验室提供解释性咨询。该核心通过以下方式提高了糖尿病研究的生产力：a）提供单个实验室无法提供的服务，B）允许研究人员专注于自己的项目，而无需开发自己的组织学和免疫过氧化物酶 3）鼓励共享这一核心设施资源的调查人员之间的互动。