Non-contact ECG Monitoring System for Detection of Atrial Fibrillation

用于检测心房颤动的非接触式心电图监测系统

• 批准号: 7109635
• 负责人: Neil J McDonald
• 金额: $ 12万
• 依托单位: QUASAR, INC.
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-30 至 2008-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7109635
• 关键词: atrial fibrillation; biomedical equipment development; biosensor device; biotechnology; clinical research; clinical trials; diagnostic tests; electrocardiographic monitor; electrocardiography; electrodes; evaluation /testing; human subject; mathematics; quality of life; questionnaires

DESCRIPTION (provided by applicant): The aim of the proposed research is to show that a new class of wearable bioelectric sensor can enhance the effectiveness of long-term monitoring of atrial fibrillation. The public health burden of atrial fibrillation is enormous and is expected to increase significantly in ensuing decades due to the increased number of elderly in the population. Long-term electrocardiographic monitoring is frequently required to determine the efficacy of antiarrhythmic therapies. However, the monitoring techniques currently employed are all invasive, and are based upon the use resistive contact electrodes that are ill-suited for long-term monitoring. This program will address issues with current monitoring techniques by developing a system for long-term electrocardiographic monitoring, based upon a novel non-contact technology, which has the revolutionary property of measuring bioelectric potentials without skin preparation, without regard to skin conductivity or amount of hair, and even through fabric. Two series of tests will be performed to compare the new bioelectrode technology with conventional electrodes: the first will involve monitoring of patients at risk of arrhythmias, and the second will quantify the bioelectrode's performance under various subject ambulatory motion. The first series of tests will be conducted at New Mexico Heart Institute under the auspices of Dr. Chris Wyndham and Dr. Luis Constantin. The second series of tests will be conducted in the laboratory at QUASAR under controlled conditions. The proposed research will offer the possibility of collecting long-term EGG data without significantly changing a subject's lifestyle, and will be a valuable tool for arrhythmia specialists, hospitals, clinics and other monitoring facilities by enabling them to become more efficient and accurate in the clinical monitoring of patients, with increased patient compliance.

描述（由申请人提供）：拟议的研究的目的是表明，一类新的可穿戴生物电感传感器可以增强房颤长期监测的有效性。心房颤动的公共卫生负担巨大，由于人口中老年人的数量增加，随后几十年中预计将大大增加。经常需要使用长期心电图监测来确定抗心律失常疗法的功效。但是，当前使用的监测技术都是侵入性的，并且基于不适合长期监测的使用电阻接触电极。该计划将通过开发一种基于新型的非接触技术来开发用于长期心电图监测的系统，以解决当前监测技术的问题，该系统具有革命性的革命性，即无需皮肤制备，而无需考虑皮肤电导率或头发的数量，甚至通过织物，它具有革命性的特性。将进行两种测试，以将新的生物电极技术与常规电极进行比较：第一个将涉及监测患有心律不齐风险的患者，第二个将在各种受试者的卧床运动下量化生物电极的表现。第一个测试将在克里斯·温德姆（Chris Wyndham）博士和路易斯·康斯坦丁（Luis Constantin）博士的主持下在新墨西哥州心脏研究所（New Mexico Heart Institute）进行。第二系列的测试将在可控条件下在类星体的实验室进行。 拟议的研究将提供收集长期鸡蛋数据的可能性，而不会显着改变受试者的生活方式，并通过提高患者依从性，使其在患者的临床监测中变得更加有效，更准确，成为心律不齐专家，医院，诊所和其他监测机构的宝贵工具。