Improved design of effective anti-cancer therapies via multiscale modelling and simulations

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The aim of this project is to elucidate the interplay between the tumour microenvironment features and the efficacy of blood and drug delivered intravascularly through suitable anti-cancer therapies based on the application of an external (electro-magnetic) field. The student will obtain new mathematical models obtained via homogenisation techniques to describe the biophysical system at hand at a tissue scale level whilst retaining information concerning the tumour microstructure. Model's predictions will support the optimisation of therapy in terms of dosage and scheduling.