Effective Treatments for Underserved Perinatal Women

描述（由申请人提供）：围产期妇女在怀孕期间和产后继续遭受精神疾病的折磨。虽然治疗方案在一定程度上有所增加，但很少有实证研究评估产褥期治疗的疗效。此外，对于如何向贫穷和得不到充分服务的妇女提供可接受和可行的基于经验的服务，几乎一无所知。这份提案概述了我在这些直接的病人护理研究领域继续工作的计划，以及我鼓励和促进初级临床科学家发展的计划，他们现在或将要直接与我一起进行这项研究。这些活动都与K-24面向患者研究的中期职业研究者奖的项目描述相一致，该奖项强调了该奖项的目标是鼓励处于职业生涯中期的临床科学家投入更多时间进行面向患者的研究，并使处于职业生涯中期的临床科学家能够投入时间指导初级临床研究者。具体目标包括：1)指导从事以患者为导向研究的初级临床研究者。2)扩展我目前在围产期心理健康方面的治疗结果和服务研究，重点是社会心理干预以及将社会心理干预与药物结合起来的研究。3)扩展我目前在人际心理治疗新应用方面的治疗发展和结果研究。4)扩展我目前在躯体化障碍患者的治疗和管理方面的研究，重点是社会心理和综合治疗干预。

DESCRIPTION (provided by applicant): Perinatal women continue to suffer from psychiatric illnesses during pregnancy and the postpartum. Though treatment options have increased to some degree, there are few empirical studies evaluating the efficacy of treatments during the puerperium. Moreover, almost nothing is known about how to provide acceptable and feasible empirically based services to indigent and underserved women. This proposal outlines my plans to continue to my work in these areas of direct patient care research, and my plans to encourage and facilitate the development of junior clinician-scientists who are, or who will be, working directly with me to conduct this research. These activities are all consistent with the program description for the K-24 Mid-Career Investigator Award in Patient-Oriented Research, which highlights that the objectives of the award are to encourage mid-career clinician scientists to devote more time to patient oriented research, and to enable mid-career clinician scientists to devote time to mentoring beginning clinical investigators. Specific Aims include: 1) Mentoring beginning clinical investigators who are engaged in patient-oriented research. 2) Extending my current treatment outcome and services research in perinatal mental health, with an emphasis on psychosocial interventions and those which combine psychosocial interventions with medication. 3) Extending my current treatment development and outcome research in new applications of Interpersonal Psychotherapy. 4) Extending my current research regarding the treatment and management of patients with somatizing disorders, with an emphasis on psychosocial and combined treatment interventions.