Functional dissection of a unique DEAD-box helicase; target for antivirals
Functional dissection of a unique DEAD-box helicase; target for antivirals
批准号:
nhmrc : GNT1157053
负责人:
金额:
$65.75万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2019
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2019-01-01 至 --
中文摘要
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英文摘要
Our aim is better understand the function of a host cell protein that is required for the replication of HIV-1, hepatitis C, Japanese encephalitis virus, West Nile virus and dengue virus. This host cell protein is a proven druggable target to limit viral infection, and yet we understand little of how it works. Our results will inform the development of novel broad-spectrum antiviral therapeutics.
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